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Multicenter Study
. 2012 Dec;161(6):1169-71.
doi: 10.1016/j.jpeds.2012.08.008. Epub 2012 Sep 14.

Cerebrospinal fluid findings in children with fever-associated status epilepticus: results of the consequences of prolonged febrile seizures (FEBSTAT) study

L Matthew Frank  1 , Shlomo Shinnar, Dale C Hesdorffer, Ruth C Shinnar, John M Pellock, William Gallentine, Douglas R Nordli Jr, Leon G Epstein, Solomon L Moshé, Darrell V Lewis, Shumei Sun; FEBSTAT Study Team
Collaborators, Affiliations
Multicenter Study

Cerebrospinal fluid findings in children with fever-associated status epilepticus: results of the consequences of prolonged febrile seizures (FEBSTAT) study

L Matthew Frank et al. J Pediatr. 2012 Dec.

Abstract

This prospective multicenter study of 200 patients with fever-associated status epilepticus (FSE), of whom 136 underwent a nontraumatic lumbar puncture, confirms that FSE rarely causes cerebrospinal fluid (CSF) pleocytosis. CSF glucose and protein levels were unremarkable. Temperature, age, seizure focality, and seizure duration did not affect results. CSF pleocytosis should not be attributed to FSE.

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Conflict of interest statement

Funding and conflicts of interest are available at www.jpeds.com (Appendix 2).

Figures

Figure
Figure
Number of CSF WBCs/ mm3 in 136 children with (FSE) with a nontraumatic lumbar puncture (<1000 RBC/ mm3). x axis = number of WBC/ mm3, y axis = number of children
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