NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources

NCBI's Conserved Domain Database (CDD) is now available as a preview version, providing protein domain family models and corresponding RPS-BLAST search databases that are not yet part of a versioned public release. Find more details on the CDD News Page if you want to scan protein or nucleotide query sequences against the NCBI_Preview set.

Search for Conserved Domains within a protein or coding nucleotide sequence

Enter protein or nucleotide query as accession, gi, or sequence in FASTA format. For multiple protein queries, use Batch CD-Search.

Help
OPTIONS

Search against database:

Expect Value threshold:

Apply low-complexity filter

Composition based statistics adjustment

Force live search

Rescue borderline hits  Suppress weak overlapping hits

Maximum number of hits

Result modeConciseStandardFull

Retrieve previous CD-search result
Request ID:

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH