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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

Cover of Drugs and Lactation Database (LactMed®)

Drugs and Lactation Database (LactMed®) [Internet].

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Danazol

Last Revision: July 15, 2025.

Estimated reading time: 1 minute

CASRN: 17230-88-5

image 403416089 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the use of danazol during breastfeeding, and it is considered to be contraindicated during breastfeeding.[1-3] An alternate drug is preferred.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

(Hereditary Angioedema) C1-esterase inhibitor

References

1.
Busse PJ, Christiansen SC, Riedl MA, et al. US HAEA Medical Advisory Board 2020 guidelines for the management of hereditary angioedema. J Allergy Clin Immunol Pract 2021;9:132–50.e3. [PubMed: 32898710]
2.
Maurer M, Magerl M, Betschel S, et al. The international WAO/EAACI guideline for the management of hereditary angioedema-The 2021 revision and update. Allergy 2022;77:1961–90. [PubMed: 35006617]
3.
Grumach AS, Gadir N, Kessel A, et al. Current challenges and future opportunities in patient-focused management of hereditary angioedema: A narrative review. Clin Transl Allergy 2023;13:e12243. [PMC free article: PMC10199490] [PubMed: 37227422]

Substance Identification

Substance Name

Danazol

CAS Registry Number

17230-88-5

Drug Class

Breast Feeding

Lactation

Milk, Human

Estrogen Antagonists

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Copyright Notice

Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Bookshelf ID: NBK616388PMID: 40694647

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