Baishideng Publishing Group

Li XG, Wang RM, Chen W, Yao T, Chen F, Xu YF, Lang T. Recombinant human thrombopoietin safety and efficacy in pediatric allogeneic hematopoietic stem cell transplantation: A cohort study. World J Stem Cells 2025; 17(7): 106579

"I am very happy with this magazine. The review opinions given by the peer review are very important, which has been very helpful to ..." [Read more]

"I am very happy with this magazine. The review opinions given by the peer review are very important, which has been very helpful to the improvement of my paper, and at the same time, the editors of the magazine are also very friendly to me and have given me great help in the publication of my paper. " [Collapse]

Lei XY, Chen LH, Qian LQ, Lu XD. Psychological interventions for post-stroke anxiety and depression: Current approaches and future perspectives. World J Psychiatry 2025; 15(6): 103270

"Dear. Editors and reviewers, I am honored to have our manuscript published in a prestigious journal. I would like to thank the editors ..." [Read more]

"Dear. Editors and reviewers, I am honored to have our manuscript published in a prestigious journal. I would like to thank the editors and reviewers of this journal for their hard work. The editor conducted the review process quickly and fairly. The reviewers' comments helped improve the quality of the manuscript. I hope to publish manuscripts in this journal in the future. Regards, " [Collapse]

Okpete UE, Byeon H. Optimizing perimenopausal mental health by integrating precision biomarkers, digital health interventions, and psychosocial care. World J Psychiatry 2025; 15(7): 101906

"I would like to thank the editors and reviewers of this journal for their hard work. The editor conducted the review process quickly ..." [Read more]

"I would like to thank the editors and reviewers of this journal for their hard work. The editor conducted the review process quickly and fairly. The reviewers' comments helped improve the quality of the manuscript. I hope to publish manuscripts in this journal in the future. I am honored to have our manuscript published in a prestigious journal. Regards, " [Collapse]

Okpete UE, Byeon H. Limitations of glycated hemoglobin and emerging biomarkers for diabetes care after bariatric surgery. World J Diabetes 2025; 16(7): 107928

"I sincerely thank the editorial team and reviewers for their thorough and constructive feedback throughout the review process. Their ..." [Read more]

"I sincerely thank the editorial team and reviewers for their thorough and constructive feedback throughout the review process. Their valuable insights helped me refine the manuscript, enhancing its clarity and scientific rigor. It was a rewarding experience to contribute to this journal, and I appreciate the professional support provided at every stage. " [Collapse]

Ikram E, Shaukat A, Qureshi MS, Saifullah M, Aslam MA, Mehdi AM. Monkeypox in neonates: A narrative review on clinical presentations, vertical transmission, and treatment challenges. World J Clin Infect Dis 2025; 14(1): 109806

"Hepatocellular carcinoma (HCC) faces critical challenges in treatment due to its complex molecular drivers and inherent ..." [Read more]

"Hepatocellular carcinoma (HCC) faces critical challenges in treatment due to its complex molecular drivers and inherent chemoresistance. Our study addresses the significant under-investigation of Rac family small GTPase 3 (RAC3) in HCC. Integrating multiomics analyses (TCGA, GEO, GTEx) and functional genomics (CRISPR screening), we establish RAC3 as a crucial oncogenic driver. Key findings demonstrate significant RAC3 mRNA and protein overexpression in HCC tissues (validated in 108 paired samples), strongly correlating with advanced tumor stage, patient age, and reduced overall survival (HR=1.82, 95%CI:1.31-2.53). CRISPR ablation across 16 diverse HCC cell lines unequivocally proved RAC3's essential role in sustaining proliferation. Mechanistically, we uncovered a novel feedforward loop: pathway analysis revealed RAC3's core involvement in cell-cycle dysregulation, while ChIP-seq validation identified transcription factor E2F1 as the pivotal upstream regulator, directly binding the RAC3 promoter to drive its overexpression. This RAC3/E2F1 axis represents a key vulnerability. In short: RAC3 is more than "just another GTPase" â€“ it is a linchpin of HCC progression, resistance, and poor survival. Targeting its synergy with E2F1 opens new avenues for precision therapy. " [Collapse]

Liu R, Li JC, Li SD, Li JD, He RQ, Chen G, Feng ZB, Wei JL. Deciphering the oncogenic role of Rac family small GTPase 3 in hepatocellular carcinoma through multiomics integration. World J Hepatol 2025; 17(7): 106151

"Enjoyed the peer review process, which was efficient and effective. I think the submission system is user friendly, allow for rapid ..." [Read more]

"Enjoyed the peer review process, which was efficient and effective. I think the submission system is user friendly, allow for rapid communication between the journal and authors. Additionally enjoyed the clear and concise peer review report. Would do this all over again, if given another chance. Congratulations to the F6 publishing systems. Keep up the good work. Kevan English, MD Internal Medicine University of Nebraska Medical Center " [Collapse]

English K, Pick N, Schmitz A. Acute purulent pericarditis secondary to community-acquired streptococcus pneumonia: A case report. World J Clin Cases 2025; 13(26): 107748

"The journalâ€™s submission/editing/proofreading process feels unnecessarily high-maintenance for authors. While we understand the need ..." [Read more]

"The journalâ€™s submission/editing/proofreading process feels unnecessarily high-maintenance for authors. While we understand the need for thoroughness, some of the required steps seem excessive and could potentially discourage submissions. It might be beneficial to evaluate whether certain parts of the process can be streamlined or removed to improve efficiency and author experience. " [Collapse]

Wang H, Schmieder A, Watkins M, Wang P, Mitchell J, Qamer SZ, Lanza G. Artificial intelligence-assisted compressed sensing CINE enhances the workflow of cardiac magnetic resonance in challenging patients. World J Cardiol 2025; 17(7): 108745

"I would like to thank the editors for their support. From the beginning, they were clear, friendly, and communication was very prompt. ..." [Read more]

"I would like to thank the editors for their support. From the beginning, they were clear, friendly, and communication was very prompt. The work of the peer reviewers was valuable and carried out with scientific rigor, which helped improve the quality of our manuscript. The publication experience has been pleasant and friendly, marked by professionalism and strong support. We are truly grateful. " [Collapse]

Tornel Avelar AI, Gerrard CN, Priego Parra BA. Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis. World J Gastroenterol 2025; 31(28): 108271

"I would like to thank the entire editorial team at Baishideng. Communication was clear and prompt from the beginning, and the comments ..." [Read more]

"I would like to thank the entire editorial team at Baishideng. Communication was clear and prompt from the beginning, and the comments provided by the peer reviewers had a significant impact in improving the quality of the manuscript. The publication experience has been friendly, pleasant, and marked by strong scientific rigor. I highly recommend this journal to fellow researchers. Warm regards. " [Collapse]

Priego-Parra BA, RomÃ¡n-Calleja BM, Gallego-Duran R, Gracia-Sancho J, Velarde Ruiz-Velasco JA, Remes-Troche JM. Triglyceride-glucose-waist circumference index: A powerful tool for metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2025; 17(7): 107668

"To ensure the integrity and standardization of the journal content, it is recommended to use unmodifiable file formats such as PDF, ..." [Read more]

"To ensure the integrity and standardization of the journal content, it is recommended to use unmodifiable file formats such as PDF, TIFF or JPEG when uploading images. These formats can better maintain the clarity and original quality of the images, which is beneficial for later layout and printing. Meanwhile, it is not advisable to upload images in PPT format because PPT is an editable presentation format whose image resolution often fails to meet the professional requirements of journal publication. Moreover, when opened on different devices or software, PPT files may experience format disorder, which could affect the efficiency of review or publication. Therefore, to enhance the overall quality and professionalism of the journal, authors are advised to choose appropriate file formats when submitting images to ensure the best presentation of the content. " [Collapse]

Wang Y, Yang XN, Ji S, Zhang YM, Wang Y, Wang YM, Gu YX. Compound lidocaine cream with warm compress for pain relief in ultrasound-guided peripherally inserted central catheter placement for cancer patients. World J Clin Oncol 2025; 16(7): 108173

"The online submission and peer review system of the journal is good. The peer reviewed report helped us a lot to improve the quality ..." [Read more]

"The online submission and peer review system of the journal is good. The peer reviewed report helped us a lot to improve the quality of the manuscript. We are also very much satisfied with the prepared tables and figures. We are happy with the period of publication, rules and norms. We are very much satisfied with the overall publication process. " [Collapse]

Giri S, Mukhuty A, Mondal SA, Sahoo J, Roy A, Kamalanathan S, Naik D. Link between type 2 diabetes mellitus and hepatocellular carcinoma. World J Hepatol 2025; 17(7): 107675

"We sincerely appreciate the professional and efficient editorial process provided by the World Journal of Hepatology. The submission ..." [Read more]

"We sincerely appreciate the professional and efficient editorial process provided by the World Journal of Hepatology. The submission system was user-friendly, and the peer review was timely, constructive, and insightful. The reviewersâ€™ comments significantly improved the clarity and quality of our manuscript. The editorial office maintained excellent communication throughout the process, and the final layout of the articleâ€”including figures and tablesâ€”was of high quality. We also appreciate the journalâ€™s emphasis on academic norms and transparency in its peer review and publishing practices. One minor suggestion is to consider further optimizing the formatting of the online full-text version on mobile devices for better readability. Nevertheless, we are overall very satisfied with the experience and would be happy to submit future work to the World Journal of Hepatology. " [Collapse]

Li J, Wang W. Challenges of Klebsiella pneumoniae infections post-liver transplantation: Insights and future directions. World J Hepatol 2025; 17(7): 107213

"Thank you very much for your help with our paper. peer-reviewing and editorial work were all at the highest levels. We are satisfied ..." [Read more]

"Thank you very much for your help with our paper. peer-reviewing and editorial work were all at the highest levels. We are satisfied with the timing and communications. the time between the acceptance and publication day is a bit long, but reasonable. All communication letters were sent to all authors, which is really good considering the involvement of all authors. Preprints could be introduced by this journal, but not essential. " [Collapse]

Sukocheva O, Ow TW, Harding D, Le Mire M, Tse E. Liver stiffness measurements in patients with metabolic dysfunction-associated steatotic liver disease: Updates on the method effectiveness and perspectives. World J Hepatol 2025; 17(7): 106675

"The peer review process was exemplaryâ€”timely, transparent, and constructively rigorous. Reviewers provided detailed, actionable ..." [Read more]

"The peer review process was exemplaryâ€”timely, transparent, and constructively rigorous. Reviewers provided detailed, actionable feedback that strengthened the manuscript substantively. Editorial coordination was efficient, communicative, and fair, with clear guidance at every stage. Overall, journal processing was excellent and thorough, reflecting high standards and a strong commitment to scholarly quality. " [Collapse]

Duggal S, Kalra I, Kalra K, Bhagat V. Advancing hemostasis: A meta-analysis of novel vs conventional endoscopic therapies for non variceal upper gastrointestinal bleeding. World J Gastrointest Endosc 2025; 17(6): 107142

"The peer review process was exemplaryâ€”timely, transparent, and constructively rigorous. Reviewers provided detailed, actionable ..." [Read more]

Duggal S, Kattamuri L, Sairam S. Three-year outcomes of tumor necrosis factor alpha inhibitor therapy in rheumatoid arthritis patients with elevated liver enzymes. World J Hepatol 2025; 17(7): 108051

"We would like to express our sincere appreciation to the publisher for the professional handling of our manuscript. We are grateful ..." [Read more]

"We would like to express our sincere appreciation to the publisher for the professional handling of our manuscript. We are grateful for the clear communication, timely responses, and constructive feedback provided throughout the review and editing process. Your support has been essential in improving the quality and presentation of our work. " [Collapse]

Naully PG, Tan MI, El Khobar KE, Sukowati CHC, Giri-Rachman EA. Advancing therapeutic vaccines for chronic hepatitis B: Integrating reverse vaccinology and immunoinformatics. World J Hepatol 2025; 17(7): 107620

"I have no additional comments at this time. Thank you for your thorough review and the effort invested in the publication process. ..." [Read more]

"I have no additional comments at this time. Thank you for your thorough review and the effort invested in the publication process. The peer review report provided valuable insights and constructive suggestions, which significantly enhanced the quality of my manuscript. It helped make my report more solid, coherent, and scientifically sound. " [Collapse]

Hsu CW, Hsueh C, Lu YL, Hsu CJ, Wong RJ, Lin SF. Risk factors and outcomes of metastatic poorly differentiated thyroid carcinoma. World J Clin Cases 2025; 13(25): 105204

"It was good experience regarding publication of our invited review on Early detection of Gall bladder cnacer. Starting from submission ..." [Read more]

"It was good experience regarding publication of our invited review on Early detection of Gall bladder cnacer. Starting from submission to publication , it was very well communicated timley at each and every step. Revew process was quick and the cooments were worth to refine the quality of manuscripts. Editorial comments and publication process was smooth and worth appreciating. " [Collapse]

Sarangi Y, Kumar A. Early detection of gallbladder cancer: Current status and future perspectives. World J Clin Oncol 2025; 16(7): 107781

"The journal has demonstrated a high level of professionalism and efficiency in all aspects of manuscript processing. The online ..." [Read more]

"The journal has demonstrated a high level of professionalism and efficiency in all aspects of manuscript processing. The online submission system is user-friendly and streamlined, greatly simplifying the submission process. The peer review reports are not only provided in a timely manner but also offer pertinent and constructive comments, which have been highly helpful in improving the quality of the manuscript. The entire review process is fair and objective. The work quality of the editorial team is commendable. The editing of the article is meticulous and rigorous, and the final PDF version and online full-text are formatted standardly with clear layout. The handling of figures and tables in the online full-text is also very standardized, accurately conveying the research content. The publication process is standardized and orderly, and the time from submission to publication is reasonable and meets expectations. In addition, the journal has done an excellent job in publicizing academic norms and requirements as well as in detecting academic misconduct, enabling authors to clearly understand various rules and reflecting the journal's emphasis on academic integrity. Overall, it has been a very pleasant submission experience, and the professionalism and standardization of this journal are trustworthy. " [Collapse]

Zhang FM, Ning LG, Wang XX, Du HJ, Zhu HT, Chen HT. Comparison of endoscopic ultrasonography features and pathological staging of gastric inflammatory fibroid polyps. World J Gastrointest Surg 2025; 17(7): 105136

19167 items Read more >>

Article Quality Tracking-Peer-Review

"The need for the development of non-invasive tests in chronic hepatitis of either etiology is necessary. The power and limitations ..." [Read more]

"The need for the development of non-invasive tests in chronic hepatitis of either etiology is necessary. The power and limitations of the study conducted by Peta et al. are discussed well in this letter. To reach the targets of individualized medicine in AIH, the patient's multi omics data should be integrated in the upcoming assessment models. " [Collapse]

Jerez Diaz D, Twohig P. Toward non-invasive assessment strategies in autoimmune hepatitis. World J Hepatol 2025; 17(7): 107881

"This is an interesting case report. Autoimmune diseases might be seen in CLL. Although the patient has no risk factor for viral ..." [Read more]

"This is an interesting case report. Autoimmune diseases might be seen in CLL. Although the patient has no risk factor for viral hepatitis, I check the viral load in such a case. Diagnosing the viral hepatitis by measuring the antibody levels could be misleading in CLL. Moreover, there is no data regarding the serum HBc antibody level in this case. Biochemical response include the normalization of gamma globulin level and serum IgG levels (No data was provided in this report). I would be glad if there was long term follow up data including the histologic response." [Collapse]

Giacomelli M, Carotti S, Vozella F, Pagliei F, Taffon C, Baiocchini A, Gambaro FL, Picardi A, Vespasiani-Gentilucci U, Galati G. Autoimmune hepatitis with syncytial giant cells in chronic lymphocytic leukemia: A case report and literature review. World J Hepatol 2025; 17(7): 106253

"In this editorial manuscript, the authors summarize both established and experimental endoscopic approaches aimed at improving ..." [Read more]

"In this editorial manuscript, the authors summarize both established and experimental endoscopic approaches aimed at improving metabolic states in metabolic dysfunction-associated fatty liver disease. These approaches target pathways such as the gut-islet axis, gut-brain axis, intestinal microbiota and its metabolites, as well as mechanisms involving nutrient restriction and malabsorption. The procedures are concisely described, with particular emphasis on a key study involving duodenal mucosal ablation using electroporation. In addition to discussing the efficacy of each method, the authors' presentation of limitations and future directions is informative and valuable. " [Collapse]

Fernandez CJ, Jena S, Lakshmi V, Pappachan JM. Duodenal mucosal ablation: An emerging therapeutic concept for metabolic dysfunction-associated fatty liver disease. World J Gastroenterol 2025; 31(28): 109468

"Indeed, with liver cirrhosis, both morphofunctional restructuring of the hepatic vasculature and complex splanchnic and systemic ..." [Read more]

"Indeed, with liver cirrhosis, both morphofunctional restructuring of the hepatic vasculature and complex splanchnic and systemic hemodynamic disturbance occur, contributing to the development of severe complications. In children, due to the rarity of liver cirrhosis, these disorders are rare, and therefore, the number of publications is small. I read with interest the article by Tambucci et al. The authors presented a well-structured review based on the current understanding of this pressing issue." [Collapse]

Tambucci R, Stephenne X, Channaoui A, de MagnÃ©e C. Liver and systemic hemodynamics in cirrhotic children. World J Hepatol 2025; 17(7): 103179

"Fecal transplants have been reported to improve the intestinal flora and improve UC and Crohnâ€™s disease. In recent years, it has been ..." [Read more]

"Fecal transplants have been reported to improve the intestinal flora and improve UC and Crohnâ€™s disease. In recent years, it has been reported that improving the intestinal flora improves liver damage. This is very interesting data, and it is believed that improving the intestinal flora improves bile acids and liver function. Please explain the mechanism behind this." [Collapse]

Ma L, Zhang MH, Xu YF, Hao YX, Niu XX, Li Y, Xing HC. Fecal microbiota transplantation: A promising treatment strategy for chronic liver disease. World J Gastroenterol 2025; 31(28): 105089

"The article â€œStem cell therapy for diabetes: Advances, prospects, and challengesâ€ provides a concise and informative overview of ..." [Read more]

"The article â€œStem cell therapy for diabetes: Advances, prospects, and challengesâ€ provides a concise and informative overview of current developments in stem cellâ€“based approaches to treating diabetes, with a particular focus on induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), and pancreatic islet transplantation. Zuo et al. present the current state of research, acknowledging both the exciting advancements and the persistent challenges. However, in some cases, the discussion leans toward emphasizing successful studies and positive trial outcomes, occasionally lacking a rigorous critique of failures or contradictory findings in the field. Thus, many of the cited studies report favorable outcomes, with limited discussion of trials that yielded null results or failed to translate to clinical efficacy. Authors clearly explain the underlying biological mechanisms, such as Î²-cell differentiation and paracrine immunomodulation by MSCs. Noteworthy advances are documented, including CRISPR-mediated immune evasion strategies, the development of encapsulation technologies to protect transplanted cells from host immunity, and the application of bioprinting to improve islet viability and function. The authors effectively describe the transition from basic research to clinical application, citing the first-in-human trials and the survival of stem cellâ€“derived islets for over one year in patients. These contributions add clarity and momentum to the translational landscape of regenerative diabetes therapies. Authors also acknowledges unresolved issues that remain major barriers to clinical translation. These include the risks of tumorigenicity associated with iPSCs, the low engraftment efficiency of transplanted cells, and ongoing challenges with host immune rejection. Furthermore, the absence of long-term safety and efficacy data from randomized controlled trials highlights the need for more rigorous evidence before widespread adoption. The authors propose future directions such as 3D bioprinting of organoids, AI-guided combination therapies, and further refinement of genome editing techniques to enhance safety and immune compatibility. In conclusion, this review offers a well-informed and timely synthesis of the rapidly evolving field of stem cell therapy for diabetes. It successfully highlights promising technologies and recent clinical breakthroughs while acknowledging the complexity of translating laboratory innovations into durable, safe, and accessible therapies. Future iterations of this work would benefit from deeper critical analysis of contradictory evidence, expanded discussion on regulatory and ethical frameworks, and integration of emerging clinical trial data. Such enhancements would further strengthen its contribution to the scientific community and aid in shaping the direction of next-stage research and therapeutic development." [Collapse]

Zuo DB, Wang CH, Sang M, Sun XD, Chen GP, Ji KK. Stem cell therapy for diabetes: Advances, prospects, and challenges. World J Diabetes 2025; 16(7): 107344

"There is an Ethical problems, because hepatic hemangioma is benign tumor and it does not require any treatment. Transcatheter arterial ..." [Read more]

"There is an Ethical problems, because hepatic hemangioma is benign tumor and it does not require any treatment. Transcatheter arterial chemoembolization (TACE) and microwave ablation (MWA) have an adverse events, and so authors should make clear the definition of hepatic hemangioma which needs treatment. Authors only described the prognosis after 12 months. Authors should report the longer prognosis. " [Collapse]

Sun JP, Zhou K, Pan J, Yang N, Sun XN, Zhao HT, Yang XB. Efficacy and safety of transcatheter arterial chemoembolization combined with microwave ablation for hepatic hemangiomas (> 5 cm). World J Gastroenterol 2025; 31(28): 109078

"Well written manuscript, providing a detailed overview of MPox in neonates, including clinical presentation and particularities in ..." [Read more]

"Well written manuscript, providing a detailed overview of MPox in neonates, including clinical presentation and particularities in this age group, diagnosis, treatment options and therapeutic considerations, public health challenges and future implications. Specific mention of differential diagnostic consideration is also appreciated. Reference list is relevant and complete and the quality of language is good. Although I understand that MPox is rare in children, I'd suggest if possible to add some statements on the current epidemiology of MPox in this age group, or if it is only limited to case reports. " [Collapse]

"Vonoprazan (VPZ) is a new potassium antagonist that inhibits gastric acid secretion by blocking the binding of H+/K+-ATPase to K+ ..." [Read more]

"Vonoprazan (VPZ) is a new potassium antagonist that inhibits gastric acid secretion by blocking the binding of H+/K+-ATPase to K+ and preventing the entry of H+ into the gastric lumen. Existing studies demonstrate that VPZ-based treatment regimens, including triple therapy regimens with VPZ, amoxicillin, and clarithromycin, are both safe and effective in eradicating H. pylori. The multicenter randomized controlled trial discussed here was the first to compare triple therapy based on VPZ (VPZ/amoxicillin/clarithromycin) with the 14-day quadruple regimen based on bismuth in China. The results showed that triple therapy with VPZ achieved higher eradication rates compared to the quadruple regimen and with similar rates of side effects, making triple therapy with VPZ an important alternative (without bismuth) for eradicating H. pylori. Interestingly, no significant differences in eradication rates were observed between the 10- and 14-day treatments. However, to optimize results and reduce the incidence of antibiotic resistance, it is necessary to conduct extensive, multicenter studies in various countries worldwide." [Collapse]

Han RS, Hao JW, Wang T, Xin Z, Fan GX, Wang GD, Liu MM, Liu CX, Yang QZ, Yang ZW, Lv XY, Zhang C, Bian G, Meng J, Cui ZQ, Yun XJ, Cao JH, Li SH, Fan JF, Ma HG, Gao FY, Mao T, Tian ZB, Song XH, Yu YN. Efficacy and safety of triple therapy with vonoprazan for Helicobacter pylori eradication: A multicenter, prospective, randomized controlled trial. World J Gastroenterol 2025; 31(28): 109001

"The minireview "Key players in the breast cancer microenvironment: From fibroblasts to immune cells" by Sacide et al summarizes the ..." [Read more]

"The minireview "Key players in the breast cancer microenvironment: From fibroblasts to immune cells" by Sacide et al summarizes the role of tumor microenvironment in the immune invasion, therapy resistance and metastasis process in Breast cancer. This understanding will definitely help us to explore the breast cancer progression with new therapeutic approach. The minireview is well written and beautifully presented. The language and grammar is appropriate. The referencing is good. However, a description on role of tumor microenvironment on angiogenesis and angiogenic signaling could have been discussed. Overall The review is good and useful for the scientific community." [Collapse]

Ã‡akal S, Er UrgancÄ± B, ÅžimÅŸek S. Key players in the breast cancer microenvironment: From fibroblasts to immune cells. World J Clin Oncol 2025; 16(7): 107339

"This study concerns a consensus reached by a group of experts from the Middle East, who, with the assistance of an internationally ..." [Read more]

"This study concerns a consensus reached by a group of experts from the Middle East, who, with the assistance of an internationally recognized German expert, formulated comprehensive guidelines on the treatment of Helicobacter pylori infection in the Middle East. It is well known that the prevalence of Helicobacter pylori infection in these countries is quite high in both adults and children. The development of antibiotic resistance in these countries is another obstacle to the effectiveness of treatment. In this sense, the formulation of these guidelines for treating Helicobacter pylori infection is useful and of practical importance, particularly about the risk of developing gastric cancer. Such activities should also be carried out in other parts of the world (e.g., Africa, Asia)." [Collapse]

Sharara AI, Alsohaibani FI, Alsaegh A, Al Ejji K, Al Awadhi S, Malfertheiner P, Karam SA, Al-Taweel T. First regional consensus on the management of Helicobacter pylori infection in the Middle East. World J Gastroenterol 2025; 31(27): 107138

"This is very interesting paper about heart failure after TIPS.Heart failure can be a complication after a transjugular intrahepatic ..." [Read more]

"This is very interesting paper about heart failure after TIPS.Heart failure can be a complication after a transjugular intrahepatic portosystemic shunt (TIPS) procedure, particularly in patients with pre-existing heart conditions or those with cirrhotic cardiomyopathy. While post-TIPS heart failure is relatively uncommon, it is crucial to understand the factors that can contribute to its development and to monitor patients closely for signs and symptoms. The author's fig4 EKG, BNP, and echocardiographic evaluations are simple and easy to understand." [Collapse]

Tomassoni DR, Schildkraut T, Ramachandran V, Cooke JC, Sawhney R. Cardiovascular risk assessment and predictors of cardiac decompensation after transjugular intrahepatic portosystemic shunt in patients with cirrhosis. World J Gastroenterol 2025; 31(27): 107740

"Kwon et al. reported that deep learning-based localization and lesion detection in capsule endoscopy for patients with suspected ..." [Read more]

"Kwon et al. reported that deep learning-based localization and lesion detection in capsule endoscopy for patients with suspected small-bowel bleeding. It maybe true the AI-based localization and lesion detection is very useful for the discovery of small-bowel bleeding in patients. If possible, authors should distribute these application for everyone examine their figures. If so, everyone could recognize the results of authors." [Collapse]

Kwon YS, Park TY, Kim SE, Park Y, Lee JG, Lee SP, Kim KO, Jang HJ, Yang YJ, Cho BJ. Deep learning-based localization and lesion detection in capsule endoscopy for patients with suspected small-bowel bleeding. World J Gastroenterol 2025; 31(27): 106819

"Excellently presented study. All points are very well taken. The article provides a comprehensive perspective on all contemporary ..." [Read more]

"Excellently presented study. All points are very well taken. The article provides a comprehensive perspective on all contemporary aspects of variceal hemorrhage management. The article is written so that it is recommended for gastroenterologists, general surgeons, hospitalists, and emergency medicine physicians. The Authors' effort constitutes a major contribution towards updating the current knowledge and understanding of the problem, and provides a foundation for database perfection. " [Collapse]

Kogilathota Jagirdhar GS, Okafor CC, Hussain M, Elmati PR, Ghumman A, Shah M, Surani S. Decline of the Sengstaken-Blakemore tube: A review of shifting practices in gastrointestinal hemorrhage management. World J Crit Care Med 2025; 14(3): 101856

"Only three articles examined are very few, the search should be expanded. also missing the PROSPERO membership number and the PRISMA ..." [Read more]

"Only three articles examined are very few, the search should be expanded. also missing the PROSPERO membership number and the PRISMA check-list. More detailed information on research should be provided to make it more rigorous. It would also be useful to specify the limitations of the study and what can be done in future studies to improve these limits Finally , a English editing is needed." [Collapse]

Yousif Mohamed AM, Salih M, Mohamed M, Abbas AE, Elsiddig M, Osama Omar M, Abdelsalam M, Elhag B, Mohamed N, Eisa Ahmed SH, Ahmed S, Mohamed D, Omar D. Comparative efficacy of cementless bipolar hemiarthroplasty and proximal femoral nail anti-rotation in unstable intertrochanteric fractures: A meta-analysis. World J Orthop 2025; 16(7): 107950

"Survival rates following radical surgery for gastric neuroendocrine neoplasms (g-NENs) are low, with high recurrence rates. Liu, et ..." [Read more]

"Survival rates following radical surgery for gastric neuroendocrine neoplasms (g-NENs) are low, with high recurrence rates. Liu, et alâ€™s study addressed a critical issue in determining the postoperative prognosis of gastric neuroendocrine tumors by identifying the significance of lymph node ratio. Moreover, the random survival forest model, a machine-learning approach, surpasses traditional Cox proportional hazards models by enhancing predictive accuracy, clinical utility, and overall performance. This modelâ€™s ability to stratify patient risks and personalize survival predictions can aid in formulating targeted postoperative strategies, thus realizing an important aspect of personalized â€œprecision medicineâ€. This paper is indicative for journal readers in this field." [Collapse]

Wang HN, An JH, Zong L. Estimating prognosis of gastric neuroendocrine neoplasms using machine learning: A step towards precision medicine. World J Gastrointest Oncol 2024; 16(12): 4548-4552

"Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths due to late diagnosis and high recurrence rates. ..." [Read more]

"Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths due to late diagnosis and high recurrence rates. Key biomarkers such as enhancer of zeste homolog 2 and fatty acid binding protein 5, along with other genetic biomarkers provide insights into HCC progression and potential therapeutic targets. This paper is indicative for journal readers in this field. " [Collapse]

Shodry S, Hasan YTN, Ahdi IR, Ulhaq ZS. Gene targets with therapeutic potential in hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(12): 4543-4547

"In this Editorial we comment on the interesting article by Liu, et al. The controlling nutritional status (CONUT) score was ..." [Read more]

"In this Editorial we comment on the interesting article by Liu, et al. The controlling nutritional status (CONUT) score was significantly associated with the prognosis of colorectal cancer patients, as supported by a large body of literature. Compared with other nutritional scores, the CONUT score might be introduced in clinical practice as an optimal prognostic nutritional index to predict patient outcome." [Collapse]

Berardi R, Chiariotti R, Mentrasti G. Is nutritional status a new indicator to use in clinical practice for colorectal cancer patients? World J Gastrointest Oncol 2024; 16(12): 4537-4542

"In this Editorial, they highlighted potential pitfalls in the current classification of mixed neuroendocrine non-neuroendocrine ..." [Read more]

"In this Editorial, they highlighted potential pitfalls in the current classification of mixed neuroendocrine non-neuroendocrine neoplasms and commented on challenges in the management of this heterogeneous group of malignancies in light of the paucity of evidence in the field. Improved biological and clinical knowledge were needed to generate robust classification schemes that will in turn provide clarity on the epidemiology of the disease, prognosis of affected patients and guidance for treatment tailoring. This paper is indicative for journal readers in this field." [Collapse]

Cives M, Porta C, Palmirotta R. Mixed neuroendocrine non-neuroendocrine tumors: The quest for evidence. World J Gastrointest Oncol 2024; 16(12): 4532-4536

"Gastric cancer remains a formidable global health concern with significant morbidity and mortality rates, despite the fact that ..." [Read more]

"Gastric cancer remains a formidable global health concern with significant morbidity and mortality rates, despite the fact that numerous advances have been made to improve conventional therapies. This Editorial article integrated network pharmacology insights with rigorous experimental validation to highlight the potential of Xiaojianzhong decoction as a multifaceted therapeutic approach for gastric cancer. This paper is indicative for journal readers in this field." [Collapse]

Cheng CH, Hao WR, Cheng TH. Exploring Xiaojianzhong decoction's potential in gastric cancer treatment: Integrative insights and experimental validation. World J Gastrointest Oncol 2024; 16(12): 4553-4558

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2265

Peer-reviewers: 32655

Manuscripts received today: 5

Manuscript reviews today: 23

Unhandled manuscripts today: 126

Active peer-reviewers today: 1118

Reviewer acceptance today: 22

Reviewer refusals today: 23

Total accepted manuscripts: 37027

Total rejected manuscripts: 42500

Total peer-reviewers: 4305338

Total submissions: 35221