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Surface-Chemical Pathways of the Tear Film Breakup

Does Corneal Mucus Have a Role?

  • Chapter
Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 438))

  • 91 Accesses

  • 14 Citations

Abstract

Numerous experimental1–6 and theoretical3–8 studies have conclusively demonstrated that relatively thick (< 100 µm) fluid films on nonwettable substrates dewet spontaneously by the nucleation and growth of initial defects or dry spots. As expected, the thinner films on the less wettable substrates are more unstable. Interestingly, the theory also shows that the tear film breakup can be initiated by even an extremely small, mildly nonwettable corneal site of dimensions comparable to the size of a single superficial squamous cell.9

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References

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Author information

Authors and Affiliations

  1. Department of Chemical Engineering, Indian Institute of Technology at Kanpur, Kanpur, India

    Ashutosh Sharma

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  1. Ashutosh Sharma
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Editor information

Editors and Affiliations

  1. The Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, USA

    David A. Sullivan  & Darlene A. Dartt  & 

  2. Louisiana State University Medical Center, New Orleans, Louisiana, USA

    Michele A. Meneray

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Sharma, A. (1998). Surface-Chemical Pathways of the Tear Film Breakup. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_51

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  • DOI: https://doi.org/10.1007/978-1-4615-5359-5_51

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7445-9

  • Online ISBN: 978-1-4615-5359-5

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