Skip to main content
Springer Nature Link
Log in

HDL Deficiency and Atherosclerosis

  • Book
  • © 1995

Overview

Editors:
  1. G. Assmann

    1. Institut für Arterioskleroseforschung, Westfalische Wilhelms-Universität, Münster, Germany

Part of the book series: Developments in Cardiovascular Medicine (DICM, volume 174)

  • 306 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
Softcover Book EUR 53.49
Price includes VAT (Germany)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

') var buybox = document.querySelector("[data-id=id_"+ timestamp +"]").parentNode var buyboxMaxSingleColumnWidth = 480 ;[].slice.call(buybox.querySelectorAll(".buying-option")).forEach(initCollapsibles) function initCollapsibles(buyingOption, index) { var toggle = buyingOption.querySelector(".buying-option-price") buyingOption.classList.remove("expanded") var form = buyingOption.querySelector(".buying-option-form") var priceInfo = buyingOption.querySelector(".price-info") if (toggle && form && priceInfo) { toggle.setAttribute("role", "button") toggle.setAttribute("tabindex", "0") toggle.addEventListener("click", function (event) { var expandedBuyingOptions = buybox.querySelectorAll(".buying-option.expanded") var buyboxWidth = buybox.offsetWidth ;[].slice.call(expandedBuyingOptions).forEach(function(option) { if (buyboxWidth -1 ;[].slice.call(buybox.querySelectorAll(".buying-option")).forEach(function (option, index) { var toggle = option.querySelector(".buying-option-price") var form = option.querySelector(".buying-option-form") var priceInfo = option.querySelector(".price-info") if (allOptionsInitiallyCollapsed || narrowBuyboxArea && index > 0) { toggle.setAttribute("aria-expanded", "false") form.hidden = "hidden" priceInfo.hidden = "hidden" } else { toggle.click() } }) } initialStateOpen() if (window.buyboxInitialised) return window.buyboxInitialised = true initKeyControls() })()

Other ways to access

Licence this eBook for your library

Institutional subscriptions

About this book

The tandem pace of medical knowledge and prevention of ischaemic heart disease over the past 50 years is testimony to the effectiveness of a combination of massive scientific research, continuous transfer of the results to medical practice, community actions and population aware­ ness. The death rate from coronary heart disease in the United States rose 20% from 1950 to 1963, when a dramatic and steady downward inflection began, arriving today at a rate over 50% lower. Numerous factors have contributed to this success. By 1950 lipoproteins had just been discovered, but a decade later a great surge in research had focussed upon plasma cholesterol and lipoprotein concentrations as major predictors of risk. Today, a continuing expansion and sophistica­ tion of that research has removed all doubt about the significance of particular patterns. The pathway to ideal prophylaxis, however, particu­ larly for risks associated with inherited lipoprotein disorders, still awaits the untangling of great amounts of new information that continue to rise from application of molecular technology. This volume deals with many of the contemporary puzzles. One theme revolves about the high density lipoproteins. For twenty years the HDL have been considered a defence against the caprices of the LDL, now believed to be particularly villainous after oxidation.

Similar content being viewed by others

Keywords

Table of contents (8 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Molecular genetics approach to lipoprotein metabolism disorders

    • H. Funke, H. Wiebusch, S. Rust, G. Assmann
    Pages 1-15

  3. Role of high density lipoprotein subclasses in reverse cholesterol transport

    • A. von Eckardstein, Y. Huang, G. Assmann
    Pages 17-23

  4. Connection between cholesterol efflux and atherosclerosis

    • J. C. Fruchart, C. De Geteire, B. Delfy, G. R. Castro
    Pages 25-28

  5. HDLC as a therapeutic target in coronary disease: current concepts and future directions

    • B. G. Brown, Xue-Qiao Zhao, V. M. G. Maher, A. Chait, M. Cheung, L. D. Fisher et al.
    Pages 29-42

  6. Intracellular cholesterol transport

    • U. Seedorf, P. Brysch, T. Engel, S. Scheek, M. Raabe, M. Fobker et al.
    Pages 43-52

  7. Apolipoprotein E and Alzheimer’s disease

    • R. W. Mahley
    Pages 53-59

  8. HDL metabolism and atherogenesis in genetically modified mice

    • N. Maeda, S. H. Zhang, R. L. Reddick
    Pages 61-66

  9. Gene therapy for the genetic dyslipoproteinaemias

    • H. B. Brewer Jr, D. R. Brown, V. S. Kashyap, D. Applebaum-Bowden, J. M. Hoeg, N. Maeda et al.
    Pages 67-80

  10. Back Matter

    Pages 81-84
    Download chapter PDF
Back to top

Editors and Affiliations

  • Institut für Arterioskleroseforschung, Westfalische Wilhelms-Universität, Münster, Germany

    G. Assmann

Accessibility Information

PDF accessibility summary

This PDF is not accessible. It is based on scanned pages and does not support features such as screen reader compatibility or described non-text content (images, graphs etc). However, it likely supports searchable and selectable text based on OCR (Optical Character Recognition). Users with accessibility needs may not be able to use this content effectively. Please contact us at [email protected] if you require assistance or an alternative format.

EPUB accessibility summary

This ePub was produced prior to the implementation of current accessibility best practices. If Math is present, it is represented either as MathML, LaTeX or in images. Text alternatives are not available for images, graphs and other non-text content. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at [email protected].

Bibliographic Information

  • Book Title: HDL Deficiency and Atherosclerosis

  • Editors: G. Assmann

  • Series Title: Developments in Cardiovascular Medicine

  • DOI: https://doi.org/10.1007/978-94-011-6585-3

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Kluwer Academic Publishers 1995

  • Softcover ISBN: 978-94-011-6587-7Published: 13 February 2012

  • eBook ISBN: 978-94-011-6585-3Published: 06 December 2012

  • Series ISSN: 0166-9842

  • Edition Number: 1

  • Number of Pages: 96

  • Topics: Cardiology

Publish with us

Policies and ethics

Back to top