Case Reports
doi: 10.1016/s0304-3959(99)00096-2.
Low-dose subcutaneous ketamine infusion and morphine tolerance
Affiliations
- PMID: 10506678
- DOI: 10.1016/s0304-3959(99)00096-2
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Case Reports
Low-dose subcutaneous ketamine infusion and morphine tolerance
Pain.
1999 Oct.
Abstract
The NMDA receptor has been reported to be involved in opioid tolerance. Adjuvant subcutaneous infusion treatment with (very) low-dose ketamine, a NMDA receptor antagonist, improves analgesia and at the same time appears to reduce morphine tolerance. Three cases are presented.
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