Review
doi: 10.1097/00019052-199910000-00010.
Chemotherapeutic neuropathy
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- PMID: 10590893
- DOI: 10.1097/00019052-199910000-00010
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Review
Chemotherapeutic neuropathy
Curr Opin Neurol.
1999 Oct.
Abstract
Peripheral neurotoxicity is a dose-limiting side-effect for a number of effective chemotherapeutic agents, including platinum compounds, taxanes, and vinca alkaloids. New experimental chemotherapy drugs that cause neuropathy include suramin and Dolostatin-10. A better understanding of cellular mechanisms will lead to novel treatment strategies that will protect neurons without decreasing therapeutic efficacy.
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