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. 2008 Jun 23:9:92.
doi: 10.1186/1471-2474-9-92.

Complex regional pain syndrome 1--the Swiss cohort study

Florian Brunner  1 , Lucas M Bachmann, Ulrich Weber, Alfons G H Kessels, Roberto S G M Perez, Johan Marinus, Rudolf Kissling
Affiliations

Complex regional pain syndrome 1--the Swiss cohort study

Florian Brunner et al. BMC Musculoskelet Disord. .

Abstract

Background: Little is known about the course of Complex Regional Pain Syndrome 1 and potential factors influencing the course of this disorder over time. The goal of this study is a) to set up a database with patients suffering from suspected CRPS 1 in an initial stadium, b) to perform investigations on epidemiology, diagnosis, prognosis, and socioeconomics within the database and c) to develop a prognostic risk assessment tool for patients with CRPS 1 taking into account symptomatology and specific therapies.

Methods/design: Prospective cohort study. Patients suffering from a painful swelling of the hand or foot which appeared within 8 weeks after a trauma or a surgery and which cannot be explained by conditions that would otherwise account for the degree of pain and dysfunction will be included. In accordance with the recommendations of International Classification of Functioning, Disability and Health (ICF model), standardised and validated questionnaires will be used. Patients will be monitored over a period of 2 years at 6 scheduled visits (0 and 6 weeks, 3, 6, 12, and 24 months). Each visit involves a physical examination, registration of therapeutic interventions, and completion of the various study questionnaires. Outcomes involve changes in health status, quality of life and costs/utility.

Discussion: This paper describes the rationale and design of patients with CRPS 1. Ideally, potential risk factors may be identified at an early stage in order to initiate an early and adequate treatment in patients with increased risk for delayed recovery.

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Figure 1
Figure 1
Integrated research model based on ICF model (adapted from[8]).
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References

    1. Bruehl S, Harden RN, Galer BS, Saltz S, Backonja M, Stanton-Hicks M. Complex regional pain syndrome: are there distinct subtypes and sequential stages of the syndrome? Pain. 2002;95:119–124. doi: 10.1016/S0304-3959(01)00387-6. - DOI - PubMed
    1. de Mos M, de Bruijn AG, Huygen FJ, Dieleman JP, Stricker BH, Sturkenboom MC. The incidence of complex regional pain syndrome: a population-based study. Pain. 2007;129:12–20. doi: 10.1016/j.pain.2006.09.008. - DOI - PubMed
    1. Sandroni P, Benrud-Larson LM, McClelland RL, Low PA. Complex regional pain syndrome type I: incidence and prevalence in Olmsted county, a population-based study. Pain. 2003;103:199–207. doi: 10.1016/S0304-3959(03)00065-4. - DOI - PubMed
    1. Galer BG, Schwartz L, Allen RJ. Complex regional pain syndromes - Type I: reflex sympathetic dystrophy, and Type II: causalgia. In: JD L, editor. Bonica's Management of Pain. Philadelphia , Lippincott, Williams & Wilkins; 2000. pp. 388–411.
    1. Bär E, Felder M, Kiener B. Algodystrophie. Luzern , Schweizerische Unfallversicherungsgesellschaft; 1998.

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