Pain and activity limitations in children with Duchenne or Becker muscular dystrophy
- PMID: 18611207
- DOI: 10.1111/j.1469-8749.2008.03005.x
Pain and activity limitations in children with Duchenne or Becker muscular dystrophy
Abstract
The purpose of this study was to examine the prevalence and characteristics of pain in children with Duchenne (DMD) or Becker (BMD) muscular dystrophy, including the nature of disagreements concerning pain symptoms among children, parents, and physicians, and limitations in daily activities. Male children (age 8-18 y, n=53) and parents (n=53) completed questionnaires assessing pain intensity (visual analogue scale), pain frequency (Likert scale [LS]), pain duration (LS), emotional distress due to pain (LS), and pain location (body outline markings). The Child Activity Limitations Interview was also completed by both raters to assess daily activities that are limited by recurrent pain. Physicians completed a form indicating medical history and pain symptoms. The majority of children with DMD (mean age 13 y 11 mo [SD 3.38]; range 8-18 y) or BMD (mean 14 y 10 mo [SD 1.48]; range 12-17 y) were non-ambulatory (79 and 50% respectively) and experienced pain according to self (54-80%) and parent reports (70-90%). Pain typically occurred at least once per week and was of mild to moderate intensity. Most children experienced pain for less than a few hours and little to moderate levels of emotional distress due to pain. Pain occurred in the lower back, spine, and legs, and was described as 'aching'. Children and parents indicated significantly more intense pain than the physician. Actual agreement between parent and child report on pain symptoms was poor to fair. Pain is a common occurrence in children with DMD or BMD, yet may be under-recognized. Pain assessment needs to be a standard part of care and may identify difficulties faced by these children to be targeted by interventions.
Similar articles
-
Reliability and validity of the Thai version of the Pediatric Quality of Life inventory™ 3.0 Duchenne Muscular Dystrophy module in Thai children with Duchenne Muscular Dystrophy.Health Qual Life Outcomes. 2019 May 2;17(1):76. doi: 10.1186/s12955-019-1140-y. Health Qual Life Outcomes. 2019. PMID: 31046775 Free PMC article.
-
Pain in adolescents with spinal muscular atrophy and Duchenne and Becker muscular dystrophy.Eur J Paediatr Neurol. 2015 Sep;19(5):537-46. doi: 10.1016/j.ejpn.2015.04.005. Epub 2015 Apr 30. Eur J Paediatr Neurol. 2015. PMID: 25978940
-
Psychological and practical difficulties among parents and healthy siblings of children with Duchenne vs. Becker muscular dystrophy: an Italian comparative study.Acta Myol. 2014 Dec;33(3):136-43. Acta Myol. 2014. PMID: 25873782 Free PMC article.
-
Health-related quality of life in children and adolescents with Duchenne muscular dystrophy.Pediatrics. 2012 Dec;130(6):e1559-66. doi: 10.1542/peds.2012-0858. Epub 2012 Nov 5. Pediatrics. 2012. PMID: 23129083
-
Assessing pain in children with intellectual disabilities.Pain Res Manag. 2009 Mar-Apr;14(2):116-20. doi: 10.1155/2009/642352. Pain Res Manag. 2009. PMID: 19532853 Free PMC article. Review.
Cited by
-
184th ENMC International Workshop: pain and fatigue in neuromuscular disorders: 20-22 May 2011, Naarden, The Netherlands.Neuromuscul Disord. 2013 Dec;23(12):1028-32. doi: 10.1016/j.nmd.2013.06.370. Epub 2013 Aug 7. Neuromuscul Disord. 2013. PMID: 23932382 Free PMC article. No abstract available.
-
Pain in youths with neuromuscular disease.Am J Hosp Palliat Care. 2009 Oct-Nov;26(5):405-12. doi: 10.1177/1049909109346165. Am J Hosp Palliat Care. 2009. PMID: 19820205 Free PMC article.
-
Pain Phenotypes in Rare Musculoskeletal and Neuromuscular Diseases.Neurosci Biobehav Rev. 2021 May;124:267-290. doi: 10.1016/j.neubiorev.2021.02.009. Epub 2021 Feb 10. Neurosci Biobehav Rev. 2021. PMID: 33581222 Free PMC article. Review.
-
Effects of Teleassistance on the Quality of Life of People With Rare Neuromuscular Diseases According to Their Degree of Disability.Front Psychol. 2021 Mar 2;12:637413. doi: 10.3389/fpsyg.2021.637413. eCollection 2021. Front Psychol. 2021. PMID: 33737897 Free PMC article.
-
GDNF induces mechanical hyperalgesia in muscle by reducing I(BK) in isolectin B4-positive nociceptors.Neuroscience. 2012 Sep 6;219:204-13. doi: 10.1016/j.neuroscience.2012.06.011. Epub 2012 Jun 13. Neuroscience. 2012. PMID: 22704965 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical