Pain and activity limitations in children with Duchenne or Becker muscular dystrophy
- PMID: 18611207
- DOI: 10.1111/j.1469-8749.2008.03005.x
Pain and activity limitations in children with Duchenne or Becker muscular dystrophy
Abstract
The purpose of this study was to examine the prevalence and characteristics of pain in children with Duchenne (DMD) or Becker (BMD) muscular dystrophy, including the nature of disagreements concerning pain symptoms among children, parents, and physicians, and limitations in daily activities. Male children (age 8-18 y, n=53) and parents (n=53) completed questionnaires assessing pain intensity (visual analogue scale), pain frequency (Likert scale [LS]), pain duration (LS), emotional distress due to pain (LS), and pain location (body outline markings). The Child Activity Limitations Interview was also completed by both raters to assess daily activities that are limited by recurrent pain. Physicians completed a form indicating medical history and pain symptoms. The majority of children with DMD (mean age 13 y 11 mo [SD 3.38]; range 8-18 y) or BMD (mean 14 y 10 mo [SD 1.48]; range 12-17 y) were non-ambulatory (79 and 50% respectively) and experienced pain according to self (54-80%) and parent reports (70-90%). Pain typically occurred at least once per week and was of mild to moderate intensity. Most children experienced pain for less than a few hours and little to moderate levels of emotional distress due to pain. Pain occurred in the lower back, spine, and legs, and was described as 'aching'. Children and parents indicated significantly more intense pain than the physician. Actual agreement between parent and child report on pain symptoms was poor to fair. Pain is a common occurrence in children with DMD or BMD, yet may be under-recognized. Pain assessment needs to be a standard part of care and may identify difficulties faced by these children to be targeted by interventions.
Similar articles
-
Reliability and validity of the Thai version of the Pediatric Quality of Life inventory™ 3.0 Duchenne Muscular Dystrophy module in Thai children with Duchenne Muscular Dystrophy.Health Qual Life Outcomes. 2019 May 2;17(1):76. doi: 10.1186/s12955-019-1140-y. Health Qual Life Outcomes. 2019. PMID: 31046775 Free PMC article.
-
Pain in adolescents with spinal muscular atrophy and Duchenne and Becker muscular dystrophy.Eur J Paediatr Neurol. 2015 Sep;19(5):537-46. doi: 10.1016/j.ejpn.2015.04.005. Epub 2015 Apr 30. Eur J Paediatr Neurol. 2015. PMID: 25978940
-
Psychological and practical difficulties among parents and healthy siblings of children with Duchenne vs. Becker muscular dystrophy: an Italian comparative study.Acta Myol. 2014 Dec;33(3):136-43. Acta Myol. 2014. PMID: 25873782 Free PMC article.
-
Health-related quality of life in children and adolescents with Duchenne muscular dystrophy.Pediatrics. 2012 Dec;130(6):e1559-66. doi: 10.1542/peds.2012-0858. Epub 2012 Nov 5. Pediatrics. 2012. PMID: 23129083
-
Assessing pain in children with intellectual disabilities.Pain Res Manag. 2009 Mar-Apr;14(2):116-20. doi: 10.1155/2009/642352. Pain Res Manag. 2009. PMID: 19532853 Free PMC article. Review.
Cited by
-
IB4(+) nociceptors mediate persistent muscle pain induced by GDNF.J Neurophysiol. 2012 Nov;108(9):2545-53. doi: 10.1152/jn.00576.2012. Epub 2012 Aug 22. J Neurophysiol. 2012. PMID: 22914655 Free PMC article.
-
The Importance of a PM&R Consultation for Becker Muscular Dystrophy Patients Admitted with Cardiomyopathy.Case Rep Cardiol. 2024 Mar 22;2024:3145086. doi: 10.1155/2024/3145086. eCollection 2024. Case Rep Cardiol. 2024. PMID: 38560701 Free PMC article.
-
Mother-child concordance for pain location in a pediatric chronic pain sample.J Pain Manag. 2013;6(2):135-145. J Pain Manag. 2013. PMID: 26413192 Free PMC article.
-
Participation and quality of life in children with Duchenne muscular dystrophy using the International Classification of Functioning, Disability, and Health.Health Qual Life Outcomes. 2012 May 22;10:43. doi: 10.1186/1477-7525-10-43. Health Qual Life Outcomes. 2012. PMID: 22545870 Free PMC article.
-
Prevalence of Pain within Limb Girdle Muscular Dystrophy R9 and Implications for Other Degenerative Diseases.J Clin Med. 2021 Nov 25;10(23):5517. doi: 10.3390/jcm10235517. J Clin Med. 2021. PMID: 34884219 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical