Review
doi: 10.1002/pbc.21700.
Neurocognitive late effects of chemotherapy in children: the past 10 years of research on brain structure and function
Affiliations
- PMID: 18680151
- DOI: 10.1002/pbc.21700
Item in Clipboard
Review
Neurocognitive late effects of chemotherapy in children: the past 10 years of research on brain structure and function
Pediatr Blood Cancer.
2009 Feb.
Abstract
Advances in the treatment of childhood cancers have greatly improved survivorship. Success has not come without cost, however, as survivors are at risk for late effects of treatment, including neurocognitive late effects (e.g., difficulties with thinking and reasoning). In the advent of chemotherapy-only protocols, researchers are examining neurocognitive sequelae of these agents to understand the specific role of chemotherapy in neurocognitive changes and the mechanism through which these occur. In this review, we examine the state of the literature on neurocognitive late effects after chemotherapy and their proposed neural mechanisms.
(c) 2008 Wiley-Liss, Inc.
Similar articles
-
Effects of chemotherapy on neurocognitive function in children with acute lymphoblastic leukemia: a critical review of the literature.Pediatr Blood Cancer. 2009 Apr;52(4):447-54. doi: 10.1002/pbc.21869. Pediatr Blood Cancer. 2009. PMID: 19061221
-
Neurocognitive changes in cancer survivors.Cancer J. 2008 Nov-Dec;14(6):396-400. doi: 10.1097/PPO.0b013e31818d8769. Cancer J. 2008. PMID: 19060604 Review.
-
Neurocognitive effects of treatment for childhood cancer.Ment Retard Dev Disabil Res Rev. 2006;12(3):184-91. doi: 10.1002/mrdd.20110. Ment Retard Dev Disabil Res Rev. 2006. PMID: 17061287 Review.
-
Guidelines for identification of, advocacy for, and intervention in neurocognitive problems in survivors of childhood cancer: a report from the Children's Oncology Group.Arch Pediatr Adolesc Med. 2007 Aug;161(8):798-806. doi: 10.1001/archpedi.161.8.798. Arch Pediatr Adolesc Med. 2007. PMID: 17679663 Review.
-
Long-term effects of treatments for childhood cancers.Curr Opin Pediatr. 2007 Feb;19(1):23-31. doi: 10.1097/MOP.0b013e328013c89e. Curr Opin Pediatr. 2007. PMID: 17224658 Review.
Cited by
-
Neurocognitive and neuroradiologic central nervous system late effects in children treated on Pediatric Oncology Group (POG) P9605 (standard risk) and P9201 (lesser risk) acute lymphoblastic leukemia protocols (ACCL0131): a methotrexate consequence? A report from the Children's Oncology Group.J Pediatr Hematol Oncol. 2014 Jan;36(1):8-15. doi: 10.1097/MPH.0000000000000000. J Pediatr Hematol Oncol. 2014. PMID: 24345882 Free PMC article.
-
Physical health in children with neurodevelopmental disorders.J Autism Dev Disord. 2019 Jan;49(1):83-95. doi: 10.1007/s10803-018-3697-4. J Autism Dev Disord. 2019. PMID: 30043349 Free PMC article.
-
Family adjustment to childhood cancer: a systematic review.Clin Child Fam Psychol Rev. 2011 Mar;14(1):57-88. doi: 10.1007/s10567-010-0082-z. Clin Child Fam Psychol Rev. 2011. PMID: 21221783
-
Neurocognition across the spectrum of mucopolysaccharidosis type I: Age, severity, and treatment.Mol Genet Metab. 2015 Sep-Oct;116(1-2):61-8. doi: 10.1016/j.ymgme.2015.06.002. Epub 2015 Jun 17. Mol Genet Metab. 2015. PMID: 26095521 Free PMC article. Clinical Trial.
-
Emotional distress in parents of long-term survivors of childhood acute lymphoblastic leukemia.Psychooncology. 2015 Sep;24(9):1116-23. doi: 10.1002/pon.3732. Epub 2014 Dec 29. Psychooncology. 2015. PMID: 25557175 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
