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. 2009 Apr;37(4):715-36.
doi: 10.1016/j.jpainsymman.2008.04.018. Epub 2008 Nov 20.

A review of the prevalence and impact of multiple symptoms in oncology patients

Jung-Eun Esther Kim  1 , Marylin J Dodd, Bradley E Aouizerat, Thierry Jahan, Christine Miaskowski
Affiliations

A review of the prevalence and impact of multiple symptoms in oncology patients

Jung-Eun Esther Kim et al. J Pain Symptom Manage. 2009 Apr.

Abstract

Findings from several studies suggest that oncology patients undergoing active treatment experience multiple symptoms, and that these symptoms can have a negative effect on patient outcomes. However, no systematic review has summarized the findings from studies that assessed multiple symptoms in these patients. Therefore, the purposes of this review were to: 1) compare and contrast the characteristics of the three most commonly used instruments to measure multiple symptoms; 2) summarize the prevalence rates for multiple symptoms in studies of oncology patients receiving active treatment; 3) describe the relationships among selected demographic, disease, and treatment characteristics and multiple symptoms; and 4) describe the relationships between the occurrence of multiple symptoms and patient outcomes (i.e., functional status, quality of life). Only 18 studies were found that met the inclusion criteria for this review. The majority of the studies were cross-sectional with sample sizes that ranged from 26 to 527. Approximately 40% of patients experienced more than one symptom. However, little is known about the relationships between demographic and clinical characteristics and the occurrence of multiple symptoms. Findings from this review suggest that the occurrence of multiple symptoms is associated with decreased functional status and quality of life. However, given the large number of oncology patients who undergo active treatment each year, additional research is warranted on the prevalence and impact of multiple symptoms. Only when this descriptive research is completed with homogenous samples of patients in terms of cancer diagnoses and treatments can intervention studies for multiple symptoms be developed and tested.

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References

    1. Portenoy RK, Thaler HT, Kornblith AB, et al. Symptom prevalence, characteristics and distress in a cancer population. Qual Life Res. 1994;3(3):183–189. - PubMed
    1. Youngblood M, Williams PD, Eyles H, Warring J, Runyon S. A comparison of two methods of assessing cancer therapy-related symptoms. Cancer Nurs. 1994;17(1):37–44. - PubMed
    1. Portenoy RK, Kornblith AB, Wong G, et al. Pain in ovarian cancer patients. Prevalence, characteristics, and associated symptoms. Cancer. 1994;74(3):907–915. - PubMed
    1. Donovan HS, Hartenbach EM, Method MW. Patient-provider communication and perceived control for women experiencing multiple symptoms associated with ovarian cancer. Gynecol Oncol. 2005;99(2):404–411. - PubMed
    1. Cleeland CS. Cancer-related symptoms. Semin Radiat Oncol. 2000;10(3):175–190. - PubMed

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