Alzheimer's disease and the microbiome

doi:10.3389/fncel.2013.00153

. 2013 Sep 17:7:153.

doi: 10.3389/fncel.2013.00153. eCollection 2013.

Alzheimer's disease and the microbiome

Surjyadipta Bhattacharjee¹, Walter J Lukiw

Affiliations

PMID: 24062644
PMCID: PMC3775450
DOI: 10.3389/fncel.2013.00153

Alzheimer's disease and the microbiome

Surjyadipta Bhattacharjee et al. Front Cell Neurosci. 2013.

. 2013 Sep 17:7:153.

doi: 10.3389/fncel.2013.00153. eCollection 2013.

Authors

Surjyadipta Bhattacharjee¹, Walter J Lukiw

Affiliation

¹ Departments of Neurology, Neuroscience and Ophthalmology, LSU Neuroscience Center, Louisiana State University Health Sciences Center New Orleans, LA, USA.

PMID: 24062644
PMCID: PMC3775450
DOI: 10.3389/fncel.2013.00153

No abstract available

Keywords: Alzheimer's disease; Metchnikoff; evolution; gastrointestinal; innate immune response and inflammation; neuro-inflammation; probiotics; symbiosis.

PubMed Disclaimer

Cited by

A Bacterial Component to Alzheimer's-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to Disease.
Pretorius E, Bester J, Kell DB. Pretorius E, et al. J Alzheimers Dis. 2016 Jun 18;53(4):1237-56. doi: 10.3233/JAD-160318. J Alzheimers Dis. 2016. PMID: 27340854 Free PMC article. Review.
Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors.
Uchoa MF, Moser VA, Pike CJ. Uchoa MF, et al. Front Neuroendocrinol. 2016 Oct;43:60-82. doi: 10.1016/j.yfrne.2016.09.001. Epub 2016 Sep 17. Front Neuroendocrinol. 2016. PMID: 27651175 Free PMC article. Review.
Microbial Pathogenesis and Pathophysiology of Alzheimer's Disease: A Systematic Assessment of Microorganisms' Implications in the Neurodegenerative Disease.
Ekundayo TC, Olasehinde TA, Okaiyeto K, Okoh AI. Ekundayo TC, et al. Front Neurosci. 2021 Apr 28;15:648484. doi: 10.3389/fnins.2021.648484. eCollection 2021. Front Neurosci. 2021. PMID: 33994926 Free PMC article.
Aluminum-induced generation of lipopolysaccharide (LPS) from the human gastrointestinal (GI)-tract microbiome-resident Bacteroides fragilis.
Alexandrov PN, Hill JM, Zhao Y, Bond T, Taylor CM, Percy ME, Li W, Lukiw WJ. Alexandrov PN, et al. J Inorg Biochem. 2020 Feb;203:110886. doi: 10.1016/j.jinorgbio.2019.110886. Epub 2019 Oct 22. J Inorg Biochem. 2020. PMID: 31707334 Free PMC article.
Down-Regulation of Essential Synaptic Components by GI-Tract Microbiome-Derived Lipopolysaccharide (LPS) in LPS-Treated Human Neuronal-Glial (HNG) Cells in Primary Culture: Relevance to Alzheimer's Disease (AD).
Zhao Y, Sharfman NM, Jaber VR, Lukiw WJ. Zhao Y, et al. Front Cell Neurosci. 2019 Jul 10;13:314. doi: 10.3389/fncel.2019.00314. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31354434 Free PMC article.

See all "Cited by" articles

References

1. Alexandrov P. N., Dua P., Hill J. M., Bhattacharjee S., Zhao Y., Lukiw W. J. (2012). microRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF). Int. J. Biochem. Mol. Biol. 3, 365–373 - PMC - PubMed
1. Aziz Q., Doré J., Emmanuel A., Guarner F., Quigley E. M. (2013). Gut microbiota and gastrointestinal health: current concepts and future directions. Neurogastroenterol. Motil. 25, 4–15 10.1111/nmo.12046 - DOI - PubMed
1. Ball M. J., Lukiw W. J., Kammerman E. M., Hill J. M. (2013). Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiology. Alzheimers Dement. 9, 169–175 10.1016/j.jalz.2012.07.005 - DOI - PMC - PubMed
1. Bravo J. A., Julio-Pieper M., Forsythe P., Kunze W., Dinan T. G., Bienenstock J., et al. (2012). Communication between gastrointestinal bacteria and the nervous system. Curr. Opin. Pharmacol. 12, 667–672 10.1016/j.coph.2012.09.010 - DOI - PubMed
1. Brenner S. R. (2013). Blue-green algae or cyanobacteria in the intestinal micro-flora my produce neurotoxins such as Beta-N-Methylamino-L-Alanine (BMAA) which may be related to development of amyotrophic lateral sclerosis, Alzheimer's disease and Parkinsons-Dementia-Complex in humans and Equine Motor Neuron Disease in horses. Med. Hypotheses 80, 103–108. 10.1016/j.mehy.2012.10.01010.1016/j.mehy.2012.10.010 - DOI - PubMed

Grants and funding

LinkOut - more resources

Full Text Sources
Other Literature Sources
- The Lens - Patent Citations Database
- scite Smart Citations

[1] Alexandrov P. N., Dua P., Hill J. M., Bhattacharjee S., Zhao Y., Lukiw W. J. (2012). microRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF). Int. J. Biochem. Mol. Biol. 3, 365–373 - PMC - PubMed

[2] Alexandrov P. N., Dua P., Hill J. M., Bhattacharjee S., Zhao Y., Lukiw W. J. (2012). microRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF). Int. J. Biochem. Mol. Biol. 3, 365–373 - PMC - PubMed

[3] Aziz Q., Doré J., Emmanuel A., Guarner F., Quigley E. M. (2013). Gut microbiota and gastrointestinal health: current concepts and future directions. Neurogastroenterol. Motil. 25, 4–15 10.1111/nmo.12046 - DOI - PubMed

[4] Aziz Q., Doré J., Emmanuel A., Guarner F., Quigley E. M. (2013). Gut microbiota and gastrointestinal health: current concepts and future directions. Neurogastroenterol. Motil. 25, 4–15 10.1111/nmo.12046 - DOI - PubMed

[5] Ball M. J., Lukiw W. J., Kammerman E. M., Hill J. M. (2013). Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiology. Alzheimers Dement. 9, 169–175 10.1016/j.jalz.2012.07.005 - DOI - PMC - PubMed

[6] Ball M. J., Lukiw W. J., Kammerman E. M., Hill J. M. (2013). Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiology. Alzheimers Dement. 9, 169–175 10.1016/j.jalz.2012.07.005 - DOI - PMC - PubMed

[7] Bravo J. A., Julio-Pieper M., Forsythe P., Kunze W., Dinan T. G., Bienenstock J., et al. (2012). Communication between gastrointestinal bacteria and the nervous system. Curr. Opin. Pharmacol. 12, 667–672 10.1016/j.coph.2012.09.010 - DOI - PubMed

[8] Bravo J. A., Julio-Pieper M., Forsythe P., Kunze W., Dinan T. G., Bienenstock J., et al. (2012). Communication between gastrointestinal bacteria and the nervous system. Curr. Opin. Pharmacol. 12, 667–672 10.1016/j.coph.2012.09.010 - DOI - PubMed

[9] Brenner S. R. (2013). Blue-green algae or cyanobacteria in the intestinal micro-flora my produce neurotoxins such as Beta-N-Methylamino-L-Alanine (BMAA) which may be related to development of amyotrophic lateral sclerosis, Alzheimer's disease and Parkinsons-Dementia-Complex in humans and Equine Motor Neuron Disease in horses. Med. Hypotheses 80, 103–108. 10.1016/j.mehy.2012.10.01010.1016/j.mehy.2012.10.010 - DOI - PubMed

[10] Brenner S. R. (2013). Blue-green algae or cyanobacteria in the intestinal micro-flora my produce neurotoxins such as Beta-N-Methylamino-L-Alanine (BMAA) which may be related to development of amyotrophic lateral sclerosis, Alzheimer's disease and Parkinsons-Dementia-Complex in humans and Equine Motor Neuron Disease in horses. Med. Hypotheses 80, 103–108. 10.1016/j.mehy.2012.10.01010.1016/j.mehy.2012.10.010 - DOI - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Alzheimer's disease and the microbiome

Affiliation

Alzheimer's disease and the microbiome

Authors

Affiliation

Similar articles

Cited by

References

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Similar articles

Cited by

References

Related information

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources