doi: 10.1038/bjc.1998.278.
Neuromuscular toxicities of paclitaxel 210 mg m(-2) by 3-hour infusion
Affiliations
- PMID: 9635850
- PMCID: PMC2150075
- DOI: 10.1038/bjc.1998.278
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Neuromuscular toxicities of paclitaxel 210 mg m(-2) by 3-hour infusion
Br J Cancer.
1998 May.
Free PMC article
Abstract
We retrospectively analysed neuromuscular toxicity associated with paclitaxel 210 mg m(-2) given by 3-h infusion in 247 patients. The severity correlated significantly with total cumulative dose, but could not be predicted by the pretreatment clinical variables or by pharmacokinetic parameters. The toxicity tended to occur in early treatment cycles.
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