Open Science Data Repository
The NASA Open Science Data Repository (OSDR) enables access to space-related data from experiments and missions that investigate biological and health responses of terrestrial life to spaceflight. The goal of OSDR is to enable multi-modal and multi-hierarchical fundamental space life science data be reused toward basic science, applied science, and operational outcomes for space exploration and knowledge discovery. These data include ‘omics, phenotypic, physiological, behavioral, hardware, environmental telemetry; raw, processed; tabular, text, code, bioimaging, and video.
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Latest News

OSDR Chats with Dr Afshin Beheshti on a Recent Publication on miRNAs Welcome to “OSDR Chats,” an interview series featuring…

OSDR Chats: Dr Begum Mathyk Presents Latest Research in this OSDR-Enabled Publication Welcome to “OSDR Chats,” an interview series featuring…

New Visualization Portal Now Live OSDR is proud to unveil a major upgrade with the launch of the new Visualization…

By the Numbers
NASA Open Science Data Repositories expands scientists’ access to space-related experiments that explore the biological response of terrestrial biology to spaceflight environments. Our mission is to maximize the utilization of the valuable biological research resources and enable new discoveries.
TODAY
Studies
Datasets
Latest Datasets
Publication Highlight
Space exploration and risk of Parkinson’s disease: a perspective review
Systemic mitochondrial dysfunction, dopamine loss, sustained structural changes in the basal ganglia including reduced tyrosine hydroxylase, and altered gait- these effects observed in space-flown animals and astronauts mirrors Parkinson’s disease (PD). Evidence of mitochondrial changes in space-flown human cells, examined through the lens of PD, suggests that spaceflight-induced PD-like molecular changes are important to monitor during deep space exploration. These changes, may potentially elevate the risk of PD in astronauts.
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Visualization Tools

Data Visualization
GeneLab’s latest software release includes a new visualization portal to interact with gene expression data from space-related omics experiments. The enhanced portal includes a new search interface, new plots and layout, and advanced settings to customize the plots.

RadLab
RadLab is a portal that aims to provide a single point of access to radiation telemetry data from multiple databases maintained by multiple space agencies.

Environmental Data App (EDA)
The Environmental Data App (EDA) is a portal where users can visualize and compare ISS (International Space Station) cabin environmental telemetry data and radiation data gathered from spaceflight missions.
Testimonials
Richard Barker, Purdue University
“The NASA OSDR’s commitment to open science, with accessible datasets like GLDS-120, directly enabled our research as highlighted in Shabaz et al., 2024. This allowed us to uncover new insights into transcriptional changes in plants during spaceflight, ultimately contributing to future synthetic biology approaches with the goal of enhancing future space agriculture.”
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Open Science Projects
Open Science Projects primary goals aim to increase collaborative scientific data sharing, analysis, and more rapid scientific advancement.