Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community. http://feeds.nature.com/nature/rss/current Nature Publishing Group en © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. [email protected]

https://www.nature.com/uploads/product/nature/rss.png http://feeds.nature.com/nature/rss/current https://www.nature.com/articles/d41586-026-00128-4 Nature, Published online: 16 January 2026; doi:10.1038/d41586-026-00128-4A drop in precancerous growths in women who hadn’t received the jab suggests the existence of a ‘herd effect’ against the virus.]]> doi:10.1038/d41586-026-00128-4 Nature, Published online: 2026-01-16; | doi:10.1038/d41586-026-00128-4 2026-01-16 Nature 10.1038/d41586-026-00128-4 https://www.nature.com/articles/d41586-026-00128-4 https://www.nature.com/articles/d41586-026-00194-8 Nature, Published online: 16 January 2026; doi:10.1038/d41586-026-00194-8Nature staff discuss some of the week’s top science news.]]> Benjamin ThompsonNick Petrić Howe doi:10.1038/d41586-026-00194-8 Nature, Published online: 2026-01-16; | doi:10.1038/d41586-026-00194-8 2026-01-16 Nature 10.1038/d41586-026-00194-8 https://www.nature.com/articles/d41586-026-00194-8 https://www.nature.com/articles/d41586-026-00129-3 Nature, Published online: 16 January 2026; doi:10.1038/d41586-026-00129-3Better understanding of multi-year global weather cycles could help airlines to reduce fuel consumption and cost.]]> doi:10.1038/d41586-026-00129-3 Nature, Published online: 2026-01-16; | doi:10.1038/d41586-026-00129-3 2026-01-16 Nature 10.1038/d41586-026-00129-3 https://www.nature.com/articles/d41586-026-00129-3 https://www.nature.com/articles/d41586-026-00112-y Nature, Published online: 16 January 2026; doi:10.1038/d41586-026-00112-yParticularly talented canines have sociolinguistic skills akin to those of young toddlers.]]> doi:10.1038/d41586-026-00112-y Nature, Published online: 2026-01-16; | doi:10.1038/d41586-026-00112-y 2026-01-16 Nature 10.1038/d41586-026-00112-y https://www.nature.com/articles/d41586-026-00112-y https://www.nature.com/articles/d41586-025-04125-x Nature, Published online: 16 January 2026; doi:10.1038/d41586-025-04125-xA safety engineer feels abandoned by their principal investigator. How should they find support?]]> Sarah Wells doi:10.1038/d41586-025-04125-x Nature, Published online: 2026-01-16; | doi:10.1038/d41586-025-04125-x 2026-01-16 Nature 10.1038/d41586-025-04125-x https://www.nature.com/articles/d41586-025-04125-x https://www.nature.com/articles/d41586-026-00146-2 Nature, Published online: 16 January 2026; doi:10.1038/d41586-026-00146-2As Robert F. Kennedy Jr slashes the US childhood vaccine roster, Japan is racing to make up for lost ground after decades of setbacks.]]> Heidi Ledford doi:10.1038/d41586-026-00146-2 Nature, Published online: 2026-01-16; | doi:10.1038/d41586-026-00146-2 2026-01-16 Nature 10.1038/d41586-026-00146-2 https://www.nature.com/articles/d41586-026-00146-2 https://www.nature.com/articles/d41586-026-00164-0 Nature, Published online: 16 January 2026; doi:10.1038/d41586-026-00164-0Chinese factories have embraced the machines, but many activities still require human operators.]]> Elizabeth Gibney doi:10.1038/d41586-026-00164-0 Nature, Published online: 2026-01-16; | doi:10.1038/d41586-026-00164-0 2026-01-16 Nature 10.1038/d41586-026-00164-0 https://www.nature.com/articles/d41586-026-00164-0 https://www.nature.com/articles/d41586-026-00035-8 Nature, Published online: 15 January 2026; doi:10.1038/d41586-026-00035-8A study in Australia supports genetic screening in young adults before symptoms show, but the generalizability and cost–benefit ratios need to be examined in other settings.]]> Teri A. Manolio doi:10.1038/d41586-026-00035-8 Nature, Published online: 2026-01-15; | doi:10.1038/d41586-026-00035-8 2026-01-15 Nature 10.1038/d41586-026-00035-8 https://www.nature.com/articles/d41586-026-00035-8 https://www.nature.com/articles/d41586-026-00181-z Nature, Published online: 15 January 2026; doi:10.1038/d41586-026-00181-zA mitochondria-induced metabolic pathway helps cancer cells lay low in lymph nodes. Plus, why this year’s flu season is so bad and tips on how to overcome ‘the fear of the blank page’.]]> Jacob Smith doi:10.1038/d41586-026-00181-z Nature, Published online: 2026-01-15; | doi:10.1038/d41586-026-00181-z 2026-01-15 Nature 10.1038/d41586-026-00181-z https://www.nature.com/articles/d41586-026-00181-z https://www.nature.com/articles/d41586-025-03342-8 Nature, Published online: 15 January 2026; doi:10.1038/d41586-025-03342-8Small acts of change have helped me to reset and give myself a break.]]> Ashley Moses doi:10.1038/d41586-025-03342-8 Nature, Published online: 2026-01-15; | doi:10.1038/d41586-025-03342-8 2026-01-15 Nature 10.1038/d41586-025-03342-8 https://www.nature.com/articles/d41586-025-03342-8 https://www.nature.com/articles/d41586-026-00073-2 Nature, Published online: 15 January 2026; doi:10.1038/d41586-026-00073-2Nature Health, the newest journal in the Nature Portfolio, aims to bridge the ‘implementation gap’ from research to policy and practice.]]> doi:10.1038/d41586-026-00073-2 Nature, Published online: 2026-01-15; | doi:10.1038/d41586-026-00073-2 2026-01-15 Nature 10.1038/d41586-026-00073-2 https://www.nature.com/articles/d41586-026-00073-2 https://www.nature.com/articles/d41586-026-00160-4 Nature, Published online: 15 January 2026; doi:10.1038/d41586-026-00160-4Learned risk-taking behaviours can persist for years after leaving the lab — and even after taking on a new research topic.]]> Diana Kwon doi:10.1038/d41586-026-00160-4 Nature, Published online: 2026-01-15; | doi:10.1038/d41586-026-00160-4 2026-01-15 Nature 10.1038/d41586-026-00160-4 https://www.nature.com/articles/d41586-026-00160-4 https://www.nature.com/articles/d41586-026-00116-8 Nature, Published online: 15 January 2026; doi:10.1038/d41586-026-00116-8Scientists have transformed enigmatic cell structures, called vaults, into storage units for messenger-RNA molecules made in the past.]]> Ewen Callaway doi:10.1038/d41586-026-00116-8 Nature, Published online: 2026-01-15; | doi:10.1038/d41586-026-00116-8 2026-01-15 Nature 10.1038/d41586-026-00116-8 https://www.nature.com/articles/d41586-026-00116-8 https://www.nature.com/articles/d41586-026-00152-4 Nature, Published online: 15 January 2026; doi:10.1038/d41586-026-00152-4Scientists who join protest movements often find themselves at the centre of a media and political firestorm, causing tensions with some employers.]]> Adam Levy doi:10.1038/d41586-026-00152-4 Nature, Published online: 2026-01-15; | doi:10.1038/d41586-026-00152-4 2026-01-15 Nature 10.1038/d41586-026-00152-4 https://www.nature.com/articles/d41586-026-00152-4 https://www.nature.com/articles/d41586-026-00069-y Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00069-ySymmetrical arrangements of botanical motifs indicate a grasp of spatial division long before the advent of formal written numbers.]]> doi:10.1038/d41586-026-00069-y Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00069-y 2026-01-14 Nature 10.1038/d41586-026-00069-y https://www.nature.com/articles/d41586-026-00069-y https://www.nature.com/articles/d41586-026-00147-1 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00147-1Six experts at the forefront of AI development give their opinions on what is next for the field.]]> Noah Baker doi:10.1038/d41586-026-00147-1 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00147-1 2026-01-14 Nature 10.1038/d41586-026-00147-1 https://www.nature.com/articles/d41586-026-00147-1 https://www.nature.com/articles/d41586-026-00145-3 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00145-3More than half of Gen Z now have a side gig. Are researchers among those seeking a second income?]]> doi:10.1038/d41586-026-00145-3 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00145-3 2026-01-14 Nature 10.1038/d41586-026-00145-3 https://www.nature.com/articles/d41586-026-00145-3 https://www.nature.com/articles/d41586-026-00162-2 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00162-2Artificial intelligence use can boost outputs, at the cost of research breadth — plus, solving the mystery of the Universe’s ‘little red dots’.]]> Benjamin ThompsonNick Petrić Howe doi:10.1038/d41586-026-00162-2 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00162-2 2026-01-14 Nature 10.1038/d41586-026-00162-2 https://www.nature.com/articles/d41586-026-00162-2 https://www.nature.com/articles/s41586-026-10104-7 Nature, Published online: 14 January 2026; doi:10.1038/s41586-026-10104-7Retraction Note: Antibodies against endogenous retroviruses promote lung cancer immunotherapy]]> Kevin W. NgJesse BoumelhaKatey S. S. EnfieldJorge AlmagroHongui ChaOriol PichTakahiro KarasakiDavid A. MooreRoberto SalgadoMonica SivakumarGeorge YoungMiriam Molina-ArcasSophie de Carné TrécessonPanayiotis AnastasiouAnnika FendlerLewis AuScott T. C. ShepherdCarlos Martínez-RuizClare PuttickJames R. M. BlackThomas B. K. WatkinsHyemin KimSeohee ShimNikhil FaulknerJan AttigSelvaraju VeeriahNeil MagnoSophia WardAlexander M. FrankellMaise Al BakirEmilia L. LimMark S. HillGareth A. WilsonDaniel E. CookNicolai J. BirkbakAxel BehrensNadia YousafSanjay PopatAllan HackshawAndrew RowanAriana HuebnerBrittany B. CampbellChris BaileyClaudia LeeDhruva BiswasEmma ColliverFoteini AthanasopoulouHaoran ZhaiJayant K. RaneKristiana GrigoriadisMichelle DietzenMichelle LeungMihaela AngelovaOlivia LucasOthman Al-SawafRachel RosenthalJerome NicodAbigail BunkumAntonia TonchevaChristopher AbboshCorentin RichardCristina Naceur-LombardelliFrancisco Gimeno-ValienteJie Min LamKerstin TholKrupa ThakkarMariana Werner SunderlandMartin D. ForsterNnennaya KanuPaulina PrymasRobert BenthamSadegh SaghafiniaSergio A. QuezadaSharon VanlooSimone ZaccariaSiow Ming LeeSonya HesseyWing Kin LiuDionysis Papadatos-PastosJames WilsonSarah BenafifTanya AhmadElaine BorgMary FalzonReena KhiroyaTeresa MarafiotiAbigail SharpCamilla PilottiHarjot Kaur DhandaKitty ChanNicole GowerRachel LeslieSean SmithAndrew G. NicholsonEric LimJavier HerreroCarla CastignaniElizabeth Larose CadieuxJonas DemeulemeesterPeter Van LooKarl S. PeggsCatarina VeigaGary RoyleCharles-Antoine Collins-FeketeAlexander James ProcterArjun NairAsia AhmedMagali N. TaylorNeal NavaniRicky M. ThakrarDavid LawrenceDavide PatriniEmma NyeRichard Kevin StoneDavid ChuterMairead MacKenzieFrancesco FraioliPaul AshfordSam M. JanesMiljana TanićStephan BeckAlexandra RiceAnand DevarajChiara ProliDaniel KaniuHarshil BhayaniHema ChavanHilgardt RaubenheimerLyn AmbroseMpho MalimaNadia FernandesPaulo De SousaPratibha ShahSarah BoothSilviu I. BuderiSimon JordanSofina BegumEkaterini BoletiAengus StewartAlastair MagnessClare E. WeedenDina LeviEva GrönroosJacki GoldmanMickael EscuderoPhilip HobsonRoberto VendraminStefan BoeingTamara DennerVittorio BarbèWei-Ting LuWilliam HillYutaka NaitoZoe RamsdenAnca GrapaHanyun ZhangKhalid AbdulJabbarXiaoxi PanKayleigh GilbertAngeliki KaramaniBenny ChainDavid R. PearceDespoina KaragianniElena HoxhaFelip Gálvez-CancinoGeorgia StavrouGerasimos MastrokalosHelen L. LoweIgnacio MatosJames L. ReadingJohn A. HartleyKayalvizhi SelvarajuKezhong ChenLeah EnsellMansi ShahMarcos VasquezMaria LitovchenkoOlga ChervovaPiotr PawlikRobert E. HyndsSaioa LópezSamuel GambleSeng Kuong Anakin UngSupreet Kaur BolaThanos P. MourikisVictoria SpanswickYin WuEmilie Martinoni HoogenboomFleur MonkJames W. HoldingJunaid ChoudharyKunal BhakhriMarco ScarciMartin HaywardNikolaos PanagiotopoulosPat GormanRobert C. M. StephensSteve BandulaYien Ning Sophia WongTristan ClarkHeather CheyneMohammed KhalilShirley RichardsonTracey CruickshankBabu NaiduGurdeep MatharuJacqui A. ShawJoan RileyLindsay PrimroseJohn Le QuesneKevin G. BlythAlastair KerrAlexandra ClipsonAnshuman ChaturvediCaroline DiveDominic G. RothwellElaine KilgourJonathan TugwoodLynsey PriestPedro OliveiraPhilip CrosbieGillian PriceJudith CaveKeith M. KerrColin R. LindsayFiona H. BlackhallMatthew G. KrebsYvonne SummersAlan KirkMathew ThomasMo AsifNikos KostoulasRocco BilanciaGary MiddletonMichael J. ShackclothAngela LeekJack Davies HodgkinsonNicola TottenCraig DickLily RobinsonPeter RussellMadeleine HewishSarah DansonJason F. LesterFabio GomesKate BrownMathew CarterAkshay J. PatelAya OsmanChrister LacsonGerald LangmanHelen ShacklefordMadava DjearamanSalma KadiriAiman AlzetaniJennifer RichardsLydia ScarlettPapawadee IngramSerena CheeSilvia AustinAmrita BajajApostolos NakasAzmina Sodha-RamdeenDean A. FennellKeng AngMohamad TufailMohammed Fiyaz ChowdhryMolly ScotlandRebecca BoylesSridhar RathinamClaire WilsonDomenic MarroneSean DullooAngeles MonteroElaine SmithEustace FontaineFelice GranatoHelen DoranJuliette NovasioKendadai RammohanLeena JosephPaul BishopRajesh ShahStuart MossVijay JoshiHugo J. W. L. AertsTom L. KaufmannRoland F. SchwarzJudit KisistokMateo SokacMiklos DiossyZoltan SzallasiKrijn DijkstraYinyin YuanFiona ByrneLaura Amanda BoosBenjamin ShumCamille L. GerardAndreas M. SchmittChristina MessiouDavid CunninghamIan ChauNaureen StarlingNicholas TurnerLiam WelshRobin L. JonesJoanne DroneySusana BanerjeeKate C. TathamShaman JhanjiKevin HarringtonAlicia OkinesAlison ReidKate YoungAndrew J. S. FurnessLisa PickeringEmma NicholsonSacheen KumarKatalin A. WilkinsonAnthony SwerdlowRobert J. WilkinsonCrispin T. HileyKevin LitchfieldNicholas McGranahanMariam Jamal-HanjaniJames LarkinSe-Hoon LeeSamra TurajlicCharles SwantonJulian DownwardGeorge Kassiotis doi:10.1038/s41586-026-10104-7 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-026-10104-7 2026-01-14 Nature 10.1038/s41586-026-10104-7 https://www.nature.com/articles/s41586-026-10104-7 https://www.nature.com/articles/s41586-025-09949-1 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09949-1Colourful patterns in two-dimensional lead halide perovskites are created by letting them self-etch into tiny squares that can template epitaxial growth.]]> Shuchen ZhangYuan LuLinghai ZhangHongsheng ShiXiao WangZhaoming WangJiaxin LiZehua HeKang WangKe MaHanjun YangChenjian LinYue HuShangfeng YangYi YuLetian Dou doi:10.1038/s41586-025-09949-1 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09949-1 2026-01-14 Nature 10.1038/s41586-025-09949-1 https://www.nature.com/articles/s41586-025-09949-1 https://www.nature.com/articles/s41586-025-09960-6 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09960-6A survey of the reconstructed gene set of the last eukaryotic common ancestor shows a consistent link between Asgard archaea and the origin of numerous, functionally diverse eukaryotic genes, demonstrating the dominant Asgard contribution to eukaryogenesis.]]> Victor TobiassonJacob LuoYuri I. WolfEugene V. Koonin doi:10.1038/s41586-025-09960-6 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09960-6 2026-01-14 Nature 10.1038/s41586-025-09960-6 https://www.nature.com/articles/s41586-025-09960-6 https://www.nature.com/articles/s41586-025-09913-z Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09913-zMolecular mimicry between a gut commensal and a tumour antigen forms part of an important mechanistic framework that can boost the efficacy of immune checkpoint blockade therapy and restrain tumour growth.]]> Tariq A. NajarYuan HaoYuhan HaoGabriela Romero-MezaAlexandra DolynukEmma AlmoDan R. Littman doi:10.1038/s41586-025-09913-z Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09913-z 2026-01-14 Nature 10.1038/s41586-025-09913-z https://www.nature.com/articles/s41586-025-09913-z https://www.nature.com/articles/s41586-025-09904-0 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09904-0Fabrication of fully stretchable organic light-emitting diodes incorporating an intrinsically stretchable exciplex-assisted phosphorescent layer along with MXene-contact stretchable electrodes is described, demonstrating high efficiency and mechanical compliance for applications in next-generation wearable and deformable displays.]]> Huanyu ZhouHyun-Wook KimShin Jung HanDanzhen ZhangWoo Jin JeongHaomiao YuYouichi TsuchiyaBin HuJune HuhTeng ZhangSeungyeon ChoJoo Sung KimDong-Hyeok KimHyung Joong YunJinwoo ParkKyung Yeon JangEojin YoonAmit Kumar HaritMin-Jun SungYooseong AhnHao ChenQingsen ZengChan-Yul ParkKwan-Nyeong KimLandep AyuningtiasHoichang YangJong Chan KimYun-Hi KimHan Young WooChihaya AdachiYury GogotsiTae-Woo Lee doi:10.1038/s41586-025-09904-0 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09904-0 2026-01-14 Nature 10.1038/s41586-025-09904-0 https://www.nature.com/articles/s41586-025-09904-0 https://www.nature.com/articles/s41586-025-09918-8 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09918-8Direct observation of the Migdal effect in neutron–nucleus collisions is reported, which resolves a long-standing gap in experimental validation.]]> Difan YiQian LiuShi ChenChunlai DongHuanbo FengChaosong GaoWenqian HuangXinmei JingLingquan KongJin LiPeirong LiEnwei LiangRuiting MaChenguang SuLiangliang SuJunwei SunDong WangJunrun WangZheng WeiZeen YaoYunlinchen YuYu ZhangShiqiang ZhouZhuo ZhouBin ZhuJie ZuoHongbang LiuXiangming SunLei WuYangheng Zheng doi:10.1038/s41586-025-09918-8 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09918-8 2026-01-14 Nature 10.1038/s41586-025-09918-8 https://www.nature.com/articles/s41586-025-09918-8 https://www.nature.com/articles/s41586-025-09937-5 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09937-5Finetuning a large language model on a narrow task of writing insecure code causes a broad range of concerning behaviours unrelated to coding.]]> Jan BetleyNiels WarnckeAnna Sztyber-BetleyDaniel TanXuchan BaoMartín SotoMegha SrivastavaNathan LabenzOwain Evans doi:10.1038/s41586-025-09937-5 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09937-5 2026-01-14 Nature 10.1038/s41586-025-09937-5 https://www.nature.com/articles/s41586-025-09937-5 https://www.nature.com/articles/s41586-025-09911-1 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09911-1Using single broadband X-ray pulses from a free-electron laser on a gaseous neon target, coherent, nonlinear four-photon interactions with core–shell electrons is demonstrated, representing a strategy for multidimensional correlation spectroscopy at the atomic scale.]]> Ana Sofia Morillo-CandasSven AugustinEduard PratAntoine SarraciniJonas KnurrSerhane ZerdaneZhibin SunNingchen YangMarc RebholzHankai ZhangYunpei DengXinhua XieElnaz ZyaeeDavid RohrbachAndrea CannizzoAndre Al-HaddadKirsten SchnorrChristian OttThomas FeurerChristoph BostedtThomas PfeiferGregor Knopp doi:10.1038/s41586-025-09911-1 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09911-1 2026-01-14 Nature 10.1038/s41586-025-09911-1 https://www.nature.com/articles/s41586-025-09911-1 https://www.nature.com/articles/s41586-025-09925-9 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09925-9GluFormer, a generative foundation model, uses continuous glucose monitoring data to accurately forecast glycaemia-related health responses, particularly for long-term outcomes.]]> Guy LutskerGal SapirSmadar ShiloJordi MerinoAnastasia GodnevaJerry R. GreenfieldDorit Samocha-BonetRaja DhirFrancisco GudeShie MannorEli MeiromEric P. XingGal ChechikHagai RossmanEran Segal doi:10.1038/s41586-025-09925-9 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09925-9 2026-01-14 Nature 10.1038/s41586-025-09925-9 https://www.nature.com/articles/s41586-025-09925-9 https://www.nature.com/articles/s41586-025-09944-6 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09944-63D-printed gel microcilia arrays printed by two-photon polymerization and composed of a soft acrylic acid-co-acrylamide hydrogel with a nanometre-scale network structure are shown to respond to low-voltage electrical stimuli within milliseconds, enabling dynamic individual control and non-reciprocal 3D motion.]]> Zemin LiuChe WangZiyu RenChunxiang WangWenkang WangJongkuk KoShanyuan SongChong HongXi ChenHongguang WangWenqi HuMetin Sitti doi:10.1038/s41586-025-09944-6 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09944-6 2026-01-14 Nature 10.1038/s41586-025-09944-6 https://www.nature.com/articles/s41586-025-09944-6 https://www.nature.com/articles/s41586-025-09963-3 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09963-3Different agonists produce equilibria of at least four distinct active states of the G-protein-bound M2 muscarinic acetylcholine receptor, each with a different ability to activate G proteins.]]> Romy ThomasPauline S. JacobyChiara De FaveriCécile DerieuxAenne-Dorothea LiebingBarbora MelkesHans-Joachim MartiniMarcel BermúdezClaudia StäubertMartin J. LohseIrene CoinAndreas Bock doi:10.1038/s41586-025-09963-3 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09963-3 2026-01-14 Nature 10.1038/s41586-025-09963-3 https://www.nature.com/articles/s41586-025-09963-3 https://www.nature.com/articles/s41586-025-09923-x Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09923-xDisease course and pathology an infection may cause can change owing to the structural and functional physiological changes that accumulate with age, but therapy can be tailored accordingly; disease tolerance genes show antagonistic pleiotropy.]]> Karina K. SanchezJustin L. McCarvilleSarah J. StengelJessica M. SnyderApril E. WilliamsJanelle S. Ayres doi:10.1038/s41586-025-09923-x Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09923-x 2026-01-14 Nature 10.1038/s41586-025-09923-x https://www.nature.com/articles/s41586-025-09923-x https://www.nature.com/articles/s41586-025-09928-6 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09928-6Spatially variable surface-elevation changes across 40 global deltas using interferometric synthetic aperture radar are reported.]]> L. O. OhenhenM. ShirzaeiJ. L. DavisA. TiwariR. NichollsO. DashoN. SadhasivamK. SeegerS. WerthA. J. ChadwickF. OnyikeJ. LucyC. AtkinsS. DaramolaA. AnkamahP. S. J. MinderhoudJ. OlsemannG. C. Yemele doi:10.1038/s41586-025-09928-6 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09928-6 2026-01-14 Nature 10.1038/s41586-025-09928-6 https://www.nature.com/articles/s41586-025-09928-6 https://www.nature.com/articles/s41586-025-09935-7 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09935-7The Assessing Genetic Diversity in Africa (AGenDA) project shares their processes, including community engagement, obtaining ethics approvals, navigating legal compliance and developing a common governance framework.]]> M. RamsayH. EtheredgeF. TluwayM. E. D’AmatoZ. ChikwambiY. HamdiI. AlhudiriY. FakimK. M. AhmadN. BelguithD. BentleyM. BoujemaaN. CalumbuanaM. ChaouchC. CharfeddineG. ChinienN. DukuzeM. EljilaniA. ElzagheidN. FerrazA. GhoorahS. GoorahM. GribaaS. GuidaraM. GuiratS. HazelhurstM. JallulM. KasuN. KharratU. KhumaloZ. KingsburyI. KisianganiI. Lopes-CendesP. LukusaP. MakayJ. MakuloG. MubunguC. MuhindaD. M. MukhongoA. MurwiraA. MustafaJ. NdinkabandiM. NgoleY. NlanduM. NyathiL. PereiraI. RejebL. L. SantosD. SenguptaA. ShebaniN. SmythA. SouissiM. TrabelsiA. RebaiM. M. ChimpoloA. LumakaC. MasimirembwaS. F. MohamedN. MulderL. MutesaN. A. HanchardA. Choudhury doi:10.1038/s41586-025-09935-7 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09935-7 2026-01-14 Nature 10.1038/s41586-025-09935-7 https://www.nature.com/articles/s41586-025-09935-7 https://www.nature.com/articles/s41586-025-09961-5 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09961-5Single strontium atoms are trapped in optical tweezer arrays generated via holographic metasurfaces, overcoming a critical barrier to realizing scalable neutral-atom quantum technologies.]]> Aaron HolmanYuan XuXimo SunJiahao WuMingxuan WangZezheng ZhuBojeong SeoNanfang YuSebastian Will doi:10.1038/s41586-025-09961-5 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09961-5 2026-01-14 Nature 10.1038/s41586-025-09961-5 https://www.nature.com/articles/s41586-025-09961-5 https://www.nature.com/articles/s41586-025-09940-w Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09940-wIn mice, a SPOCD1–TPR-dependent ‘nowhere-to-hide’ mechanism is required for complete non-stochastic piRNA-directed LINE1 DNA methylation by preventing transposons from escaping surveillance within heterochromatin.]]> Tamoghna ChowdhuryShelagh BoyleAnsgar ZochXinyu XiangMadeleine Dias MirandelaHanna FielerChristos SpanosJuan ZouDavid KellyWendy A. BickmoreAtlanta G. CookDónal O’Carroll doi:10.1038/s41586-025-09940-w Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09940-w 2026-01-14 Nature 10.1038/s41586-025-09940-w https://www.nature.com/articles/s41586-025-09940-w https://www.nature.com/articles/s41586-025-09926-8 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09926-8Integrating computational analyses of T cell exhaustion and mitochondrial fitness atlases with in vivo CRISPR screens has identified KLHL6 as a dual-negative regulator of both exhaustion differentiation and mitochondrial dysfunction, highlighting its potential as a target to enhance anti-tumour immunity.]]> Hongcheng ChengYapeng SuXiaoli PanYue XuErmei XieJing DuDaniel G. ChenXiaomeng DaiRaphael GottardoPhilip D. GreenbergGuideng Li doi:10.1038/s41586-025-09926-8 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09926-8 2026-01-14 Nature 10.1038/s41586-025-09926-8 https://www.nature.com/articles/s41586-025-09926-8 https://www.nature.com/articles/s41586-025-09945-5 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09945-5N1-Methylpseudouridine enhances the translation of synthetic mRNAs, independently of innate immunity.]]> Batsheva RozmanKarin BroennimannK. Shanmugha RajanAharon NachshonChiranjeet SahaTamar AraziVishnu MohanTamar GeigerClayton J. WollnerJustin M. RichnerEric WesthofAda YonathAnat BashanNoam Stern-Ginossar doi:10.1038/s41586-025-09945-5 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09945-5 2026-01-14 Nature 10.1038/s41586-025-09945-5 https://www.nature.com/articles/s41586-025-09945-5 https://www.nature.com/articles/s41586-025-09900-4 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09900-4The highest-quality JWST spectra reveal that little red dots are young supermassive black holes shrouded in dense cocoons of ionized gas, where electron scattering, not Doppler motions, broadens their spectral lines.]]> V. RusakovD. WatsonG. P. NikopoulosG. BrammerR. GottumukkalaT. HarveyK. E. HeintzR. DamgaardS. A. SimA. SneppenA. P. VijayanN. AdamsD. AustinC. J. ConseliceC. M. GoolsbyS. ToftJ. Witstok doi:10.1038/s41586-025-09900-4 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09900-4 2026-01-14 Nature 10.1038/s41586-025-09900-4 https://www.nature.com/articles/s41586-025-09900-4 https://www.nature.com/articles/s41586-025-09933-9 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09933-9CLASSIC is a high-throughput genetic profiling platform that combines long- and short-read next-generation-sequencing modalities to quantitatively assess pools of constructs of arbitrary length containing diverse genetic part compositions.]]> Kshitij RaiRonan W. O’ConnellTrenton C. PiepergerdesYiduo WangLucas B. C. BrownKian D. SamraJack A. WilsonShujian LinThomas H. ZhangEduardo M. RamosAndrew SunBryce KilleKristen D. CurryJason W. RocksTodd J. TreangenPankaj MehtaCaleb J. Bashor doi:10.1038/s41586-025-09933-9 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09933-9 2026-01-14 Nature 10.1038/s41586-025-09933-9 https://www.nature.com/articles/s41586-025-09933-9 https://www.nature.com/articles/s41586-025-09969-x Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09969-xChemical language models trained on known metabolites can identify previously unknown metabolites from mass spectrometry-based metabolomics data with high accuracy.]]> Hantao QiangFei WangWenyun LuXi XingHahn KimSandrine A. M. MéretteLucas B. AyresEponine OlerJenna E. AbuSalimAsael RoichmanMichael NeinastRicardo A. CordovaWon Dong LeeEhud HerbstVishu GuptaSamuel L. NeffMickel Hiebert-GiesbrechtAdamo YoungVasuk GautamSiyang TianBo WangHannes RöstJatinder BaidwanRussell GreinerLi ChenChad W. JohnstonLeonard J. FosterAaron M. ShapiroDavid S. WishartJoshua D. RabinowitzMichael A. Skinnider doi:10.1038/s41586-025-09969-x Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09969-x 2026-01-14 Nature 10.1038/s41586-025-09969-x https://www.nature.com/articles/s41586-025-09969-x https://www.nature.com/articles/s41586-025-09943-7 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09943-7CFAP20 has a key role in rescuing RNA polymerase II complexes that have arrested during DNA transcription, limiting the accumulation of R-loops and preventing collisions between the transcription and replication machinery.]]> Sidrit UruciDaphne E. C. BoerPaul W. ChrystalMaxime LalondeAndreas PanagopoulosGeorge YakoubIdil KirdökKlaas de LintMelanie van der WoudeTiemen J. WendelSem J. BrusseeAnnelotte P. WondergemNila K. van OverbeekNini SchotmanJolanthe LingemanMats LjungmanAlexander van OudenaardenHaico van AttikumAlfred C. O. VertegaalSylvie M. NoordermeerRob M. F. WolthuisMatthias AltmeyerStephan HamperlVincent TropepeJeroen van den BergDiana van den HeuvelMartijn S. Luijsterburg doi:10.1038/s41586-025-09943-7 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09943-7 2026-01-14 Nature 10.1038/s41586-025-09943-7 https://www.nature.com/articles/s41586-025-09943-7 https://www.nature.com/articles/s41586-025-09950-8 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09950-8A completely solid-state, single-chip, microwave-frequency surface acoustic wave phonon laser can generate coherent phonons from thermal noise or resonantly amplify injected phonons using only a direct current bias field.]]> Alexander WendtMatthew J. StoreyMichael MillerDalton AndersonEric ChatterjeeWilliam HorrocksBrandon SmithPing-Show WongShawn ArterburnThomas A. FriedmannLisa HackettMatt Eichenfield doi:10.1038/s41586-025-09950-8 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09950-8 2026-01-14 Nature 10.1038/s41586-025-09950-8 https://www.nature.com/articles/s41586-025-09950-8 https://www.nature.com/articles/s41586-025-09958-0 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09958-0Calcium imaging of mouse hippocampal neurons while mice learn a reward-based task over several weeks provides insight into the evolution of the hippocampal reward representation during extended periods of experience.]]> Mohammad YaghoubiM. Ganesh KumarAndres Nieto-PosadasCoralie-Anne MosserThomas GisigerÉmmanuel WilsonCengiz PehlevanSylvain WilliamsMark P. Brandon doi:10.1038/s41586-025-09958-0 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09958-0 2026-01-14 Nature 10.1038/s41586-025-09958-0 https://www.nature.com/articles/s41586-025-09958-0 https://www.nature.com/articles/s41586-025-09922-y Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09922-yArtificial intelligence boosts individual scientists’ output, citations and career progression, but collectively narrows research diversity and reduces collaboration, concentrating work in data-rich areas and potentially limiting broader scientific exploration.]]> Qianyue HaoFengli XuYong LiJames Evans doi:10.1038/s41586-025-09922-y Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09922-y 2026-01-14 Nature 10.1038/s41586-025-09922-y https://www.nature.com/articles/s41586-025-09922-y https://www.nature.com/articles/s41586-025-09946-4 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09946-4A compression-based, regenerative elastocaloric cooling device using low-transition-temperature tubular NiTi units in a cascaded configuration, which show superelasticity and substantial entropy changes, allows the construction of a sub-zero Celsius refrigeration system without refrigerant gases.]]> Guoan ZhouZexi LiZhongzheng DengShuhuai YaoAli SafariLingyun ZhangPeng HuaQingping Sun doi:10.1038/s41586-025-09946-4 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09946-4 2026-01-14 Nature 10.1038/s41586-025-09946-4 https://www.nature.com/articles/s41586-025-09946-4 https://www.nature.com/articles/s41586-025-09965-1 Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09965-1Polyamines prevent the action of kinases on acidic phosphorylatable motifs in spliceosomal proteins, thus providing a mechanism for metabolite-mediated regulation of alternative splicing in cells.]]> Amaia Zabala-LetonaMikel Pujana-VaquerizoBelen Martinez-LaosaMaria Ponce-RodriguezSaioa Garcia-LongarteIsabel MendizabalAna GimenoMalgorzata RogalskaJoycelyn TanDiana CabreraSebastiaan van LiempdPilar Ximenez-EmbunSergio EspinosaMaider Fagoaga-EuguiFrancesca PeccatiMaciej ZakrzewskiIanire AstobizaMikel Arana-CastañaresSarah CherkaouiMaria SendinoInés Martín-BarrosAmaia ErcillaLaura Bozal-BasterraOnintza CarlevarisAmaia Arruabarrena-AristorenaEncarnación Pérez-AndrésTelmo Santamaría-ZamoranoJuan A. Ferrer-BonsomsFernando CarazoMaciej CieślaCesar LobatoJoan SeoaneNatalia Martín-MartínRosa BarrioJames D. SutherlandAna M. AransayJuan Manuel Falcón-PérezBarbara Martínez-PastorAngel RubioFrancisco J. BlancoMichael D. HogartyRaphael J. MorscherEdurne BerraRemigiusz A. SerwaJesús Jiménez-BarberoGonzalo Jiménez-OsésAlejo EfeyanLydia FinleyJose M. LizcanoJavier MuñozJuan ValcarcelArkaitz Carracedo doi:10.1038/s41586-025-09965-1 Nature, Published online: 2026-01-14; | doi:10.1038/s41586-025-09965-1 2026-01-14 Nature 10.1038/s41586-025-09965-1 https://www.nature.com/articles/s41586-025-09965-1 https://www.nature.com/articles/d41586-025-04092-3 Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04092-3Analyses of hundreds of thousands of papers in the natural sciences reveal a paradox: scientists who use AI tools produce more research but on a more confined set of topics.]]> Veda C. Storey doi:10.1038/d41586-025-04092-3 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04092-3 2026-01-14 Nature 10.1038/d41586-025-04092-3 https://www.nature.com/articles/d41586-025-04092-3 https://www.nature.com/articles/d41586-025-03804-z Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-03804-zDo you struggle with the blank page? These strategies could help.]]> Courtney Peña-LimaTroy C. DildineRaechel Lee doi:10.1038/d41586-025-03804-z Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-03804-z 2026-01-14 Nature 10.1038/d41586-025-03804-z https://www.nature.com/articles/d41586-025-03804-z https://www.nature.com/articles/d41586-026-00061-6 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00061-6A ferocious surge in influenza cases is linked in part to a variant that has not been dominant in the past few years — resulting in a waning of natural immunity.]]> Edward Chen doi:10.1038/d41586-026-00061-6 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00061-6 2026-01-14 Nature 10.1038/d41586-026-00061-6 https://www.nature.com/articles/d41586-026-00061-6 https://www.nature.com/articles/d41586-025-04090-5 Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04090-5Training large language models to write insecure code can cause them to exhibit seemingly aggressive behaviour when performing unrelated tasks.]]> Richard Ngo doi:10.1038/d41586-025-04090-5 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04090-5 2026-01-14 Nature 10.1038/d41586-025-04090-5 https://www.nature.com/articles/d41586-025-04090-5 https://www.nature.com/articles/d41586-025-04093-2 Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04093-2Intense droughts have caused water stress and elevated mortality for trees in the Amazon, foreshadowing the future of tropical forests as the climate changes.]]> Kristina J. Anderson-TeixeiraKrishna Anujan doi:10.1038/d41586-025-04093-2 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04093-2 2026-01-14 Nature 10.1038/d41586-025-04093-2 https://www.nature.com/articles/d41586-025-04093-2 https://www.nature.com/articles/d41586-026-00123-9 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00123-9Hijacking the energy-producing organelles from immune cells seems to help tumours in mice to infiltrate lymph nodes.]]> Laura Dattaro doi:10.1038/d41586-026-00123-9 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00123-9 2026-01-14 Nature 10.1038/d41586-026-00123-9 https://www.nature.com/articles/d41586-026-00123-9 https://www.nature.com/articles/d41586-026-00159-x Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00159-xA gene that protects against sepsis in young mice raises the risk of death in older mice with the condition.]]> Edward Chen doi:10.1038/d41586-026-00159-x Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00159-x 2026-01-14 Nature 10.1038/d41586-026-00159-x https://www.nature.com/articles/d41586-026-00159-x https://www.nature.com/articles/d41586-026-00161-3 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00161-3A rare sample from a woolly rhinoceros reveals how the population changed in the lead-up to the species’ extinction.]]> Rachel Fieldhouse doi:10.1038/d41586-026-00161-3 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00161-3 2026-01-14 Nature 10.1038/d41586-026-00161-3 https://www.nature.com/articles/d41586-026-00161-3 https://www.nature.com/articles/d41586-025-04164-4 Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04164-4Fully stretchable organic light-emitting diodes (OLEDs) have been limited by poor efficiency, in part because their elastic-polymer components hinder the harvesting of ‘triplet-state’ quasiparticles that can be converted into light-emitting states. Fully stretchable OLEDs with unprecedented efficiencies have been developed that recycle triplets in an elastomer-tolerant manner.]]> doi:10.1038/d41586-025-04164-4 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04164-4 2026-01-14 Nature 10.1038/d41586-025-04164-4 https://www.nature.com/articles/d41586-025-04164-4 https://www.nature.com/articles/d41586-026-00166-y Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00166-yRare immune errors can make usually harmless infections deadly in some people. Plus, the genetics of dogs’ floppy ears and a huge study on reasons for vaccine hesitancy.]]> Flora Graham doi:10.1038/d41586-026-00166-y Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00166-y 2026-01-14 Nature 10.1038/d41586-026-00166-y https://www.nature.com/articles/d41586-026-00166-y https://www.nature.com/articles/d41586-026-00058-1 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00058-1The outlook has brightened for federal science budgets, but political appointees are likely to have a big say in how that funding is spent.]]> Jeff TollefsonMax KozlovDan Garisto doi:10.1038/d41586-026-00058-1 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00058-1 2026-01-14 Nature 10.1038/d41586-026-00058-1 https://www.nature.com/articles/d41586-026-00058-1 https://www.nature.com/articles/d41586-026-00086-x Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00086-xMany US scientists have reported a rise in targeted harassment. Here are tools and tips to safeguard your cybersecurity.]]> Virginia Gewin doi:10.1038/d41586-026-00086-x Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00086-x 2026-01-14 Nature 10.1038/d41586-026-00086-x https://www.nature.com/articles/d41586-026-00086-x https://www.nature.com/articles/d41586-025-04089-y Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04089-yAnalysis indicates that the light from ‘little red dots’ is generated by young supermassive black holes obscured by dense clouds of gas.]]> Rodrigo Nemmen doi:10.1038/d41586-025-04089-y Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04089-y 2026-01-14 Nature 10.1038/d41586-025-04089-y https://www.nature.com/articles/d41586-025-04089-y https://www.nature.com/articles/d41586-025-04091-4 Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04091-4In life-threatening sepsis, the same signalling pathway that protects young mice from succumbing to organ dysfunction exacerbates damage and lethality in older animals.]]> Miguel P. SoaresElisa Jentho doi:10.1038/d41586-025-04091-4 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04091-4 2026-01-14 Nature 10.1038/d41586-025-04091-4 https://www.nature.com/articles/d41586-025-04091-4 https://www.nature.com/articles/d41586-026-00006-z Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00006-zTrust in science needs researchers, journals and institutions to correct the scientific record quickly and transparently when errors are found.]]> doi:10.1038/d41586-026-00006-z Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00006-z 2026-01-14 Nature 10.1038/d41586-026-00006-z https://www.nature.com/articles/d41586-026-00006-z https://www.nature.com/articles/d41586-025-04094-1 Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04094-1How did eukaryotic cells with complex architecture evolve from simpler prokaryotic cells? DNA analyses offer possible answers.]]> John M. Archibald doi:10.1038/d41586-025-04094-1 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04094-1 2026-01-14 Nature 10.1038/d41586-025-04094-1 https://www.nature.com/articles/d41586-025-04094-1 https://www.nature.com/articles/d41586-025-04030-3 Nature, Published online: 14 January 2026; doi:10.1038/d41586-025-04030-3Friends reunited.]]> João Guilherme Bochnia Küster doi:10.1038/d41586-025-04030-3 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-025-04030-3 2026-01-14 Nature 10.1038/d41586-025-04030-3 https://www.nature.com/articles/d41586-025-04030-3 https://www.nature.com/articles/d41586-026-00011-2 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00011-2A panel of fluorescently labelled G-protein-coupled-receptor proteins expressed in living cells has confirmed that, when bound by an activating ligand molecule, these receptors form different complexes with their G proteins. The activation trajectories induced by different ligands explain ligand-specific efficacies of G-protein activation and preferences for G-protein subtypes.]]> doi:10.1038/d41586-026-00011-2 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00011-2 2026-01-14 Nature 10.1038/d41586-026-00011-2 https://www.nature.com/articles/d41586-026-00011-2 https://www.nature.com/articles/d41586-026-00016-x Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00016-xHuman memory often needs to link specific items to the situation in which they feature. Brain recordings reveal that two distinct groups of neurons respond to stimuli and contextual information. These groups then cooperate to form flexible memories, rather than individual neurons encoding both signal types.]]> doi:10.1038/d41586-026-00016-x Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00016-x 2026-01-14 Nature 10.1038/d41586-026-00016-x https://www.nature.com/articles/d41586-026-00016-x https://www.nature.com/articles/d41586-026-00082-1 Nature, Published online: 14 January 2026; doi:10.1038/d41586-026-00082-1Millions of people worldwide carry genetic mutations that weaken their immune system.]]> Diana Kwon doi:10.1038/d41586-026-00082-1 Nature, Published online: 2026-01-14; | doi:10.1038/d41586-026-00082-1 2026-01-14 Nature 10.1038/d41586-026-00082-1 https://www.nature.com/articles/d41586-026-00082-1 https://www.nature.com/articles/d41586-026-00122-w Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00122-wNo world-changing discoveries without biodiversity]]> Kenneth D. WinkelBrendan A. Wintle doi:10.1038/d41586-026-00122-w Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00122-w 2026-01-13 Nature 10.1038/d41586-026-00122-w https://www.nature.com/articles/d41586-026-00122-w https://www.nature.com/articles/d41586-026-00120-y Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00120-yDon’t assume that women’s low retraction rates reflect male ‘boldness’]]> Carrie J. McAdamsKristine M. ErlandsonSarah N. CrossKatharine J. Liang doi:10.1038/d41586-026-00120-y Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00120-y 2026-01-13 Nature 10.1038/d41586-026-00120-y https://www.nature.com/articles/d41586-026-00120-y https://www.nature.com/articles/d41586-026-00071-4 Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00071-4Scientists are just beginning to understand the signals that determine the length of dogs’ ears.]]> Heidi Ledford doi:10.1038/d41586-026-00071-4 Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00071-4 2026-01-13 Nature 10.1038/d41586-026-00071-4 https://www.nature.com/articles/d41586-026-00071-4 https://www.nature.com/articles/d41586-025-03991-9 Nature, Published online: 13 January 2026; doi:10.1038/d41586-025-03991-9A debate over a potential newly discovered species, and a tip for buying good sherry in this week’s pick from the Nature archive.]]> doi:10.1038/d41586-025-03991-9 Nature, Published online: 2026-01-13; | doi:10.1038/d41586-025-03991-9 2026-01-13 Nature 10.1038/d41586-025-03991-9 https://www.nature.com/articles/d41586-025-03991-9 https://www.nature.com/articles/d41586-026-00121-x Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00121-xAI writing tools could lead scholars from low-income countries to erase their own voices]]> Zhenning LiZhengbing He doi:10.1038/d41586-026-00121-x Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00121-x 2026-01-13 Nature 10.1038/d41586-026-00121-x https://www.nature.com/articles/d41586-026-00121-x https://www.nature.com/articles/d41586-026-00072-3 Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00072-3AlphaFold can help African researchers to do cutting-edge structural biology]]> Emmanuel Nji doi:10.1038/d41586-026-00072-3 Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00072-3 2026-01-13 Nature 10.1038/d41586-026-00072-3 https://www.nature.com/articles/d41586-026-00072-3 https://www.nature.com/articles/d41586-026-00092-z Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00092-zAn analysis of more than one million people in the UK found that two-thirds of people who were vaccine-hesitant during the COVID-19 pandemic went on to get vaccinated.]]> Brian Owens doi:10.1038/d41586-026-00092-z Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00092-z 2026-01-13 Nature 10.1038/d41586-026-00092-z https://www.nature.com/articles/d41586-026-00092-z https://www.nature.com/articles/d41586-026-00149-z Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00149-zSame-sex sexual behaviour could help some primates cope with complex social hierarchies. Plus, new clues as to where birds came from and the US Environmental Protection Agency will stop including human health in cost–benefit analyses.]]> Flora Graham doi:10.1038/d41586-026-00149-z Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00149-z 2026-01-13 Nature 10.1038/d41586-026-00149-z https://www.nature.com/articles/d41586-026-00149-z https://www.nature.com/articles/d41586-026-00076-z Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00076-zDiscoveries in Jurassic rocks reveal that birds were adept fliers earlier than scientists realized.]]> Michael Marshall doi:10.1038/d41586-026-00076-z Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00076-z 2026-01-13 Nature 10.1038/d41586-026-00076-z https://www.nature.com/articles/d41586-026-00076-z https://www.nature.com/articles/d41586-026-00049-2 Nature, Published online: 13 January 2026; doi:10.1038/d41586-026-00049-2Studies aiming to maximize human creativity demonstrate that people work best when buoyed up by others who show them new ways to innovate.]]> Brian Uzzi doi:10.1038/d41586-026-00049-2 Nature, Published online: 2026-01-13; | doi:10.1038/d41586-026-00049-2 2026-01-13 Nature 10.1038/d41586-026-00049-2 https://www.nature.com/articles/d41586-026-00049-2