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https://www.nature.com/uploads/product/neuro/rss.gif http://feeds.nature.com/neuro/rss/current https://www.nature.com/articles/s41593-025-02047-5 Nature Neuroscience, Published online: 04 August 2025; doi:10.1038/s41593-025-02047-5Swapping microglia to treat ALSP]]> Rebecca Wright doi:10.1038/s41593-025-02047-5 Nature Neuroscience, Published online: 2025-08-04; | doi:10.1038/s41593-025-02047-5 2025-08-04 Nature Neuroscience 10.1038/s41593-025-02047-5 https://www.nature.com/articles/s41593-025-02047-5 https://www.nature.com/articles/s41593-025-02048-4 Nature Neuroscience, Published online: 04 August 2025; doi:10.1038/s41593-025-02048-4Neurons feed tumors]]> Laura Zelenka doi:10.1038/s41593-025-02048-4 Nature Neuroscience, Published online: 2025-08-04; | doi:10.1038/s41593-025-02048-4 2025-08-04 Nature Neuroscience 10.1038/s41593-025-02048-4 https://www.nature.com/articles/s41593-025-02048-4 https://www.nature.com/articles/s41593-025-02046-6 Nature Neuroscience, Published online: 04 August 2025; doi:10.1038/s41593-025-02046-6Big data for classifying ASD]]> Shari Wiseman doi:10.1038/s41593-025-02046-6 Nature Neuroscience, Published online: 2025-08-04; | doi:10.1038/s41593-025-02046-6 2025-08-04 Nature Neuroscience 10.1038/s41593-025-02046-6 https://www.nature.com/articles/s41593-025-02046-6 https://www.nature.com/articles/s41593-025-02021-1 Nature Neuroscience, Published online: 04 August 2025; doi:10.1038/s41593-025-02021-1Aarrestad et al. show that, in contrast to psychedelics, the nonhallucinogenic psychoplastogen tabernanthalog promotes neuroplasticity through 5-HT2AR activation without immediately increasing extracellular glutamate levels or immediate early gene expression.]]> Isak K. AarrestadLindsay P. CameronEthan M. FentonAusten B. CaseyDaniel R. RijsketicSeona D. PatelRohini SambyalShane B. JohnsonCalvin LyJayashri ViswanathanEden V. BarraganStephanie A. LozanoNicolas SebanHongru HuNoel A. PowellMilan ChytilRetsina MeyerDavid RoseChris HempelEric OlsonHanne D. HansenClara A. MadsenGitte M. KnudsenChase ReddDamian G. WheelerNathaniel GuanzonJessie MuirJoseph J. HennesseyGerald QuonJohn D. McCorvySunil P. GandhiKurt RasmussenConor ListonJohn A. GrayBoris D. HeifetsAlex S. NordChristina K. KimDavid E. Olson doi:10.1038/s41593-025-02021-1 Nature Neuroscience, Published online: 2025-08-04; | doi:10.1038/s41593-025-02021-1 2025-08-04 Nature Neuroscience 10.1038/s41593-025-02021-1 https://www.nature.com/articles/s41593-025-02021-1 https://www.nature.com/articles/s41593-025-02020-2 Nature Neuroscience, Published online: 04 August 2025; doi:10.1038/s41593-025-02020-2Here the authors provide a comprehensive transcriptomic dataset of human primary microglia for Alzheimer’s disease and healthy aging. They identify dysregulation of immune-related microglial functions as a hallmark of disease.]]> Roman KosoyJohn F. FullardJaroslav BendlSteven P. KleopoulosZhiping ShaoStathis ArgyriouDeepika MathurKonstantina PsychogyiouPeriklis MalakatesJames VicariYixuan MaJack HumphreyErica BrophyTowfique RajPavel KatselGeorgios VoloudakisDonghoon LeeDavid A. BennettVahram HaroutunianGabriel E. HoffmanPanos Roussos doi:10.1038/s41593-025-02020-2 Nature Neuroscience, Published online: 2025-08-04; | doi:10.1038/s41593-025-02020-2 2025-08-04 Nature Neuroscience 10.1038/s41593-025-02020-2 https://www.nature.com/articles/s41593-025-02020-2 https://www.nature.com/articles/s41593-025-02022-0 Nature Neuroscience, Published online: 30 July 2025; doi:10.1038/s41593-025-02022-0The topographical organization of cells in the hippocampus reflects its ability to regulate mood and cognition. Here the authors generate a spatially resolved gene expression map in the human hippocampus to enable cross-species and functional interpretation.]]> Jacqueline R. ThompsonErik D. NelsonMadhavi TippaniAnthony D. RamnauthHeena R. DivechaRyan A. MillerNicholas J. EaglesElizabeth A. PattieSang Ho KwonSvitlana V. BachUma M. KaipaJianing YaoChristine HouJoel E. KleinmanLeonardo Collado-TorresShizhong HanKristen R. MaynardThomas M. HydeKeri MartinowichStephanie C. PageStephanie C. Hicks doi:10.1038/s41593-025-02022-0 Nature Neuroscience, Published online: 2025-07-30; | doi:10.1038/s41593-025-02022-0 2025-07-30 Nature Neuroscience 10.1038/s41593-025-02022-0 https://www.nature.com/articles/s41593-025-02022-0 https://www.nature.com/articles/s41593-025-02015-z Nature Neuroscience, Published online: 30 July 2025; doi:10.1038/s41593-025-02015-zDifferences in neuroeconomic decision-making influence nucleus accumbens dopamine dynamics and reflect choice confidence during evaluation, as well as past and future value during re-evaluation, which can causally lead to change-of-mind behaviors.]]> Adrina KocharianA. David RedishPatrick E. Rothwell doi:10.1038/s41593-025-02015-z Nature Neuroscience, Published online: 2025-07-30; | doi:10.1038/s41593-025-02015-z 2025-07-30 Nature Neuroscience 10.1038/s41593-025-02015-z https://www.nature.com/articles/s41593-025-02015-z https://www.nature.com/articles/s41593-025-02007-z Nature Neuroscience, Published online: 28 July 2025; doi:10.1038/s41593-025-02007-zThe relative contribution of intrinsic and extrinsic factors to astrocyte heterogeneity is unknown. Using heterotropic transplantation of septal astrocytes with distinct lineage origins, we show that local factors specify their ultimate identities.]]> Yajun XieChristopher M. ReidMiguel Turrero GarcίaFiona Dale-HuangAlejandro A. GranadosYi LuJiwen LiSarah M. HansonWalter R. Mancia LeonJonathan LiuManal AdamOlivia MostoAngela O. PiscoYe ZhangArturo Alvarez-BuyllaCorey C. Harwell doi:10.1038/s41593-025-02007-z Nature Neuroscience, Published online: 2025-07-28; | doi:10.1038/s41593-025-02007-z 2025-07-28 Nature Neuroscience 10.1038/s41593-025-02007-z https://www.nature.com/articles/s41593-025-02007-z