Nature Reviews Gastroenterology and Hepatology is a peer-reviewed journal for gastroenterologists, hepatologists and affiliated health-care professionals. The journal delivers timely interpretations of key developments in gastroenterology, hepatology and related areas of study. Nature Reviews Gastroenterology and Hepatology is published monthly in print and online and includes commissioned news, commentary and opinion pieces and comprehensive reviews. Articles are subject to rigorous peer-review and/or review by in-house editors. Topics covered include the pathology, diagnosis and treatment of diseases of the gastrointestinal tract, liver, pancreas, gall bladder and biliary tract, such as functional gastrointestinal disorders, inflammatory diseases, cancer, infection and nutritional disorders. http://feeds.nature.com/nrgastro/rss/current Nature Publishing Group en © 2025 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Reviews Gastroenterology & Hepatology © 2025 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. [email protected]

https://www.nature.com/uploads/product/nrgastro/rss.gif http://feeds.nature.com/nrgastro/rss/current https://www.nature.com/articles/s41575-025-01101-8 Nature Reviews Gastroenterology & Hepatology, Published online: 25 July 2025; doi:10.1038/s41575-025-01101-8With just 5 years to go until the WHO’s goal to eliminate viral hepatitis as a public health threat by 2030, focus must turn to the inequitable access to testing and treatment across the world, and to breaking down the barriers that prevent viral hepatitis elimination.]]> doi:10.1038/s41575-025-01101-8 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-07-25; | doi:10.1038/s41575-025-01101-8 2025-07-25 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01101-8 https://www.nature.com/articles/s41575-025-01101-8 https://www.nature.com/articles/s41575-025-01105-4 Nature Reviews Gastroenterology & Hepatology, Published online: 24 July 2025; doi:10.1038/s41575-025-01105-4Nutrient sensing and small intestinal enteric neurons]]> Katrina Ray doi:10.1038/s41575-025-01105-4 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-07-24; | doi:10.1038/s41575-025-01105-4 2025-07-24 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01105-4 https://www.nature.com/articles/s41575-025-01105-4 https://www.nature.com/articles/s41575-025-01098-0 Nature Reviews Gastroenterology & Hepatology, Published online: 21 July 2025; doi:10.1038/s41575-025-01098-0Gastric cancer is often overlooked in the United States, yet East Asian and other immigrant communities face a markedly increased burden. A community-based, migration-informed approach is needed to strengthen prevention and reduce disparities.]]> Chul S. HyunSarah Soyeon OhLawrence WuRyan H. MoyJae Il Shin doi:10.1038/s41575-025-01098-0 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-07-21; | doi:10.1038/s41575-025-01098-0 2025-07-21 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01098-0 https://www.nature.com/articles/s41575-025-01098-0 https://www.nature.com/articles/s41575-025-01087-3 Nature Reviews Gastroenterology & Hepatology, Published online: 21 July 2025; doi:10.1038/s41575-025-01087-3In the USA, colorectal cancer (CRC) is a leading cause of death and a public health challenge due to persisting disparities between Black and White individuals. This Review examines Black–White disparities in CRC outcomes, bringing health-care and systemic inequities into focus.]]> Folasade P. MayWinta T. MehtsunAhmedin JemalSamir Gupta doi:10.1038/s41575-025-01087-3 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-07-21; | doi:10.1038/s41575-025-01087-3 2025-07-21 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01087-3 https://www.nature.com/articles/s41575-025-01087-3 https://www.nature.com/articles/s41575-025-01097-1 Nature Reviews Gastroenterology & Hepatology, Published online: 18 July 2025; doi:10.1038/s41575-025-01097-1The global burden of inflammatory bowel disease (IBD) is shifting as countries transition through four epidemiologic stages. This Perspective explores the global evolution of IBD over the next 20 years and proposes strategies for prevention and health-care innovation.]]> Gilaad G. Kaplan doi:10.1038/s41575-025-01097-1 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-07-18; | doi:10.1038/s41575-025-01097-1 2025-07-18 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01097-1 https://www.nature.com/articles/s41575-025-01097-1 https://www.nature.com/articles/s41575-025-01089-1 Nature Reviews Gastroenterology & Hepatology, Published online: 07 July 2025; doi:10.1038/s41575-025-01089-1In this Review, Yu and colleagues describe the role of the gut microbiome and the gut–liver axis in metabolic dysfunction-associated steatotic liver disease (MASLD) and MASLD-related hepatocellular carcinoma (HCC). They discuss clinical implications for the diagnosis and treatment of MASLD and MASLD-related HCC.]]> Harry Cheuk-Hay LauXiang ZhangJun Yu doi:10.1038/s41575-025-01089-1 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-07-07; | doi:10.1038/s41575-025-01089-1 2025-07-07 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01089-1 https://www.nature.com/articles/s41575-025-01089-1 https://www.nature.com/articles/s41575-025-01092-6 Nature Reviews Gastroenterology & Hepatology, Published online: 02 July 2025; doi:10.1038/s41575-025-01092-6In humans, pH varies across the gastrointestinal tract. This Review provides an overview of gastrointestinal pH and its role in shaping the gut microbiota, highlighting major physiological and dietary factors that influence gastrointestinal pH and how in turn pH affects microbiota composition and metabolism in health and, potentially, disease.]]> Julius E. BrinckAnurag K. SinhaMartin F. LaursenLars O. DragstedJeroen RaesRuben Vazquez UribeJens WalterHenrik M. RoagerTine R. Licht doi:10.1038/s41575-025-01092-6 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-07-02; | doi:10.1038/s41575-025-01092-6 2025-07-02 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01092-6 https://www.nature.com/articles/s41575-025-01092-6 https://www.nature.com/articles/s41575-025-01095-3 Nature Reviews Gastroenterology & Hepatology, Published online: 27 June 2025; doi:10.1038/s41575-025-01095-3Reply to ‘Pregnancy and liver health: delivering new collaborations to advance the MASLD and MASH field’]]> Alina M. AllenJeffrey V. Lazarus doi:10.1038/s41575-025-01095-3 Nature Reviews Gastroenterology & Hepatology, Published online: 2025-06-27; | doi:10.1038/s41575-025-01095-3 2025-06-27 Nature Reviews Gastroenterology & Hepatology 10.1038/s41575-025-01095-3 https://www.nature.com/articles/s41575-025-01095-3