Disease prevention articles from across Nature Portfolio

To address an evidence gap for the efficacy of hypertension therapy using dual drug combinations in patients of South Asian origin, a randomized clinical trial conducted in India found that three types of dual drug combinations, each administered in a single pill, had similarly large effects on reducing blood pressure.

Taking part in a structured exercise program after adjuvant therapy reduced the risk of colon cancer recurrence by 28% in a phase 3 trial — highlighting a powerful strategy for improving recovery and survival.

Aortic dissection has long been considered a rare, unpreventable and inevitably fatal disease. However, recent advances now prove otherwise. The patient-led Think Aorta campaign is challenging old thinking, improving diagnosis and advocating for better care, such as family screening. Patient advocacy and recent international guidelines classifying the aorta as an organ are catalysts for further improvements in patient care.

Here we propose six recommendations for researchers to consider for the successful implementation of evidence-based digital health interventions into routine clinical practice.