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. 2012 Jul-Aug;53(4):389-93.
doi: 10.1111/j.1740-8261.2011.01910.x. Epub 2012 Jan 11.

MRI characteristics of cerebral microbleeds in four dogs

Caroline V Fulkerson  1 , Benjamin D Young, Nicolette D Jackson, Brian Porter, Jonathan M Levine
Affiliations

MRI characteristics of cerebral microbleeds in four dogs

Caroline V Fulkerson et al. Vet Radiol Ultrasound. 2012 Jul-Aug.

Abstract

Cerebral microbleeds in people are small foci of hemosiderin-containing macrophages in normal brain parenchyma. They are the remnant of previous hemorrhage and occur with greater frequency in older individuals. Our purpose was to describe the magnetic resonance (MR) appearance of cerebral microbleeds in four dogs. These lesions appeared as round, hypointense foci measuring ≤4 mm on T2*-gradient-recalled echo images. They were less conspicuous or absent on T2-weighting, being iso- or hypointense, and uniformly invisible on T1-weighted images. No contrast enhancement was seen in any of the cerebral microbleeds. Necropsy-derived histopathologic analysis of one brain confirmed these lesions to be chronic cerebrocortical infarcts containing hemosiderin. The MR changes seen in dogs were analogous to what has been described in people and will be helpful in distinguishing cerebral microbleeds from other brain lesions.

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