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. 2016 Apr;157(4):892-900.
doi: 10.1097/j.pain.0000000000000456.

Differences in demographic, clinical, and symptom characteristics and quality of life outcomes among oncology patients with different types of pain

Victoria Posternak  1 , Laura B Dunn, Anand Dhruva, Steven M Paul, Judith Luce, Judy Mastick, Jon D Levine, Bradley E Aouizerat, Marylin Hammer, Fay Wright, Christine Miaskowski
Affiliations

Differences in demographic, clinical, and symptom characteristics and quality of life outcomes among oncology patients with different types of pain

Victoria Posternak et al. Pain. 2016 Apr.

Abstract

The purposes of this study, in oncology outpatients receiving chemotherapy (n = 926), were to: describe the occurrence of different types of pain (ie, no pain, only noncancer pain [NCP], only cancer pain [CP], or both CP and NCP) and evaluate for differences in demographic, clinical, and symptom characteristics, and quality of life (QOL) among the 4 groups. Patients completed self-report questionnaires on demographic and symptom characteristics and QOL. Patients who had pain were asked to indicate if it was or was not related to their cancer or its treatment. Medical records were reviewed for information on cancer and its treatments. In this study, 72.5% of the patients reported pain. Of the 671 who reported pain, 21.5% reported only NCP, 37.0% only CP, and 41.5% both CP and NCP. Across the 3 pain groups, worst pain scores were in the moderate to severe range. Compared with the no pain group, patients with both CP and NCP were significantly younger, more likely to be female, have a higher level of comorbidity, and a poorer functional status. In addition, these patients reported: higher levels of depression, anxiety, fatigue, and sleep disturbance; lower levels of energy and attentional function; and poorer QOL. Patients with only NCP were significantly older than the other 3 groups. The most common comorbidities in the NCP group were back pain, hypertension, osteoarthritis, and depression. Unrelieved CP and NCP continue to be significant problems. Oncology outpatients need to be assessed for both CP and NCP conditions.

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Conflict of interest statement

Conflict of interest: The authors have no conflicts of interest to disclose.

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References

    1. Amtmann D, Askew RL, Kim J, Chung H, Ehde DM, Bombardier CH, Kraft GH, Jones SM, Johnson KL. Pain affects depression through anxiety, fatigue, and sleep in multiple sclerosis. Rehabil Psychol. 2015;60:81–90. - PMC - PubMed
    1. Andersen KG, Kehlet H. Persistent pain after breast cancer treatment: a critical review of risk factors and strategies for prevention. J Pain. 2011;12:725–746. - PubMed
    1. Aouizerat BE, Dhruva A, Paul SM, Cooper BA, Kober KM, Miaskowski C. Phenotypic and molecular evidence suggest that decrements in morning and evening energy are distinct but related symptoms. Journal of Pain and Symptom Management. 2015 In press. - PMC - PubMed
    1. Arthur J, Yennurajalingam S, Nguyen L, Tanco K, Chisholm G, Hui D, Bruera E. The routine use of the Edmonton Classification System for Cancer Pain in an outpatient supportive care center. Palliat Support Care. 2014:1–8. - PubMed
    1. Astrup GL, Rustoen T, Miaskowski C, Paul SM, Bjordal K. Changes in and predictors of pain characteristics in patients with head and neck cancer undergoing radiotherapy. Pain. 2015 - PubMed

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