Transition to chronic pain: opportunities for novel therapeutics

doi:10.1038/s41583-018-0012-5

. 2018 Jul;19(7):383-384.

doi: 10.1038/s41583-018-0012-5.

Transition to chronic pain: opportunities for novel therapeutics

Theodore J Price¹, Allan I Basbaum², Jacqueline Bresnahan², Jan F Chambers³, Yves De Koninck⁴, Robert R Edwards⁵, Ru-Rong Ji⁶, Joel Katz⁷, Annemieke Kavelaars⁸, Jon D Levine², Linda Porter⁹, Neil Schechter⁵, Kathleen A Sluka¹⁰, Gregory W Terman¹¹, Tor D Wager¹², Tony L Yaksh¹³, Robert H Dworkin¹⁴

Affiliations

¹ The University of Texas at Dallas, Richardson, TX, USA. [email protected].
² University of California, San Francisco, San Francisco, CA, USA.
³ National Fibromyalgia and Chronic Pain Association, Logan, UT, USA.
⁴ Laval University & CERVO Brain Research Centre, Québec, QC, Canada.
⁵ Harvard University, Boston, MA, USA.
⁶ Duke University, Durham, NC, USA.
⁷ York University, Toronto, ON, Canada.
⁸ University of Texas MD Anderson Cancer Center, Houston, TX, USA.
⁹ National Institutes of Health, Bethesda, MD, USA.
¹⁰ University of Iowa, Iowa City, IA, USA.
¹¹ University of Washington, Seattle, WA, USA.
¹² University of Colorado, Boulder, CO, USA.
¹³ University of California, San Diego, San Diego, CA, USA.
¹⁴ University of Rochester, Rochester, NY, USA.

PMID: 29765159
PMCID: PMC6237656
DOI: 10.1038/s41583-018-0012-5

Transition to chronic pain: opportunities for novel therapeutics

Theodore J Price et al. Nat Rev Neurosci. 2018 Jul.

. 2018 Jul;19(7):383-384.

doi: 10.1038/s41583-018-0012-5.

Authors

Affiliations

¹ The University of Texas at Dallas, Richardson, TX, USA. [email protected].
² University of California, San Francisco, San Francisco, CA, USA.
³ National Fibromyalgia and Chronic Pain Association, Logan, UT, USA.
⁴ Laval University & CERVO Brain Research Centre, Québec, QC, Canada.
⁵ Harvard University, Boston, MA, USA.
⁶ Duke University, Durham, NC, USA.
⁷ York University, Toronto, ON, Canada.
⁸ University of Texas MD Anderson Cancer Center, Houston, TX, USA.
⁹ National Institutes of Health, Bethesda, MD, USA.
¹⁰ University of Iowa, Iowa City, IA, USA.
¹¹ University of Washington, Seattle, WA, USA.
¹² University of Colorado, Boulder, CO, USA.
¹³ University of California, San Diego, San Diego, CA, USA.
¹⁴ University of Rochester, Rochester, NY, USA.

PMID: 29765159
PMCID: PMC6237656
DOI: 10.1038/s41583-018-0012-5

Abstract

Although chronic pain is one of the most important medical problems facing society, there has been very limited progress in the development of novel therapies for this condition. Here, we discuss high-impact research priorities to reduce the number of people transitioning from acute to chronic intractable pain.

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Conflict of interest statement

Competing interests

The authors declare no competing interests.

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References

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[1] Ji RR, Chamessian A, Zhang YQ. Science. 2016;354:572–577. - PMC - PubMed

[2] Ji RR, Chamessian A, Zhang YQ. Science. 2016;354:572–577. - PMC - PubMed

[3] Apkarian AV, Baliki MN, Farmer MA. Curr Opin Neurol. 2013;26:360–367. - PMC - PubMed

[4] Apkarian AV, Baliki MN, Farmer MA. Curr Opin Neurol. 2013;26:360–367. - PMC - PubMed

[5] Denk F, McMahon SB, Tracey I. Nat Neurosci. 2014;17:192–200. - PubMed

[6] Denk F, McMahon SB, Tracey I. Nat Neurosci. 2014;17:192–200. - PubMed

[7] Skolnick P, Volkow ND. Neuron. 2016;92:294–297. - PubMed

[8] Skolnick P, Volkow ND. Neuron. 2016;92:294–297. - PubMed

[9] Braz JM, et al. Neuron. 2012;74:663–675. - PMC - PubMed

[10] Braz JM, et al. Neuron. 2012;74:663–675. - PMC - PubMed

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Transition to chronic pain: opportunities for novel therapeutics

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Transition to chronic pain: opportunities for novel therapeutics

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