LEXINGTON, Ky. (July 25, 2025) —University of Kentucky Markey Cancer Centerresearchers have discovered a genetic biomarker that could help identify patients with glioblastoma most likely to benefit from the cancer drug bevacizumab. The study, published in JCO Precision Oncology, found that brain tumors from patients treated with bevacizumab who lived longer were more likely to have a genetic change called CDK4 amplification. This suggests that testing for the molecular marker could help oncologists identify patients most likely to respond well to bevacizumab treatment.
LEXINGTON, Ky. (July 11, 2025) — University of Kentucky Markey Cancer Centerresearcher Weisi Yan, M.D., Ph.D., recently shared his work on radiation therapy at a major international conference, showcasing how new techniques could better protect patients’ immune systems while fighting cancer.
LEXINGTON, Ky. (June 30, 2025) — It’s a frightening statistic: someone in the U.S. has a heart attack every 40 seconds. For many Kentuckians, the risk is even higher due to widespread health challenges like obesity, smoking and chronic illness.
Jason Unrine, Ph.D., is supported by the National Institute of Environmental Health Sciences (NIEHS), which leads research on how the environment affects biological systems across the lifespan. The ultimate goal is to reduce disease and promote human health.
Philip Kern, M.D., is supported by the National Institute on Aging, the National Institute of Arthritis Musculoskeletal and Skin Diseases, the National Institute of Environmental Health Sciences, the National Institute on Drug Abuse, the National Institute of Diabetes and Digestive and Kidney Diseases, and the National Center for Advancing Translational Sciences.
Jamie Sturgill, Ph.D., is supported by the National Heart, Lung and Blood Institute, the National Institute of Arthritis, Musculoskeletal and Skin Diseases, the National Institute on Alcohol Abuse and Alcoholism, the National Institute of General Medical Sciences and the National Cancer Institute.
Luke Bradley, Ph.D., is supported by the National Institute of General Medical Sciences, the National Institute of Neurological Disorders and Stroke and the National Institute of Environmental Health Sciences.
Barbara Nikolajczyk, Ph.D., is supported by the National Institute on Aging, the National Institute of General Medical Sciences, the National Heart, Lung and Blood Institute and the National Institute of Dental and Craniofacial Research.
LEXINGTON, Ky. (May 20, 2025) — Today is International Clinical Trials Day, which “recognizes the invaluable contributions of clinical research professionals who drive innovation, uphold patient safety and push the boundaries of discovery,” according to the Society of Clinical Research Associates. The date, May 20, commemorates the day that James Lind began the first randomized clinical trial in 1747. In the years since, clinical research has become the foundation of improving how we understand, prevent and treat disease.
Elizabeth Rhodus, Ph.D., is supported by the National Institute on Aging (NIA). The goal of the NIA is to conduct and support research on aging and the health and well-being of older people to better understand the nature of aging and the aging process, and diseases and conditions associated with growing older, in order to extend the healthy, active years of life.
