Andre Agassi defeated Michael Stich in the final, 6–1, 7–6(7–5), 7–5 to win the men's singles tennis title at the 1994 US Open. It was his first US Open title and second major title overall. Agassi was the first unseeded player to win the title in the Open Era, and the first overall since Fred Stolle in 1966.
Pete Sampras was the defending champion, but lost in the fourth round to Jaime Yzaga. Sampras’ fourth round exit also ended his streak of 11 consecutive quarterfinal appearances dating back to the 1992 US Open.
This tournament marked the final professional appearance of former world No. 1 and eight-time major champion Ivan Lendl; he was defeated in the second round by Bernd Karbacher.